Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB J Weibezahn, P Tessarz, C Schlieker, R Zahn, Z Maglica, S Lee, ... Cell 119 (5), 653-665, 2004 | 551 | 2004 |
Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK A Mogk, C Schlieker, KL Friedrich, HJ Schönfeld, E Vierling, B Bukau Journal of Biological Chemistry 278 (33), 31033-31042, 2003 | 356 | 2003 |
Roles of individual domains and conserved motifs of the AAA+ chaperone ClpB in oligomerization, ATP hydrolysis, and chaperone activity A Mogk, C Schlieker, C Strub, W Rist, J Weibezahn, B Bukau Journal of Biological Chemistry 278 (20), 17615-17624, 2003 | 308 | 2003 |
Substrate recognition by the AAA+ chaperone ClpB C Schlieker, J Weibezahn, H Patzelt, P Tessarz, C Strub, K Zeth, A Erbse, ... Nature structural & molecular biology 11 (7), 607-615, 2004 | 273 | 2004 |
Mechanisms, biology and inhibitors of deubiquitinating enzymes KR Love, A Catic, C Schlieker, HL Ploegh Nature chemical biology 3 (11), 697-705, 2007 | 263 | 2007 |
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER R Ernst, B Mueller, HL Ploegh, C Schlieker Molecular cell 36 (1), 28-38, 2009 | 246 | 2009 |
Prevention and reversion of protein aggregation by molecular chaperones in the E. coli cytosol: implications for their applicability in biotechnology C Schlieker, B Bukau, A Mogk Journal of biotechnology 96 (1), 13-21, 2002 | 222 | 2002 |
Characterization of a trap mutant of the AAA+ chaperone ClpB J Weibezahn, C Schlieker, B Bukau, A Mogk Journal of Biological Chemistry 278 (35), 32608-32617, 2003 | 183 | 2003 |
A Deubiquitinating Activity Is Conserved in the Large Tegument Protein of the Herpesviridae C Schlieker, GA Korbel, LM Kattenhorn, HL Ploegh Journal of virology 79 (24), 15582-15585, 2005 | 176 | 2005 |
Regulation of Torsin ATPases by LAP1 and LULL1 C Zhao, RSH Brown, AR Chase, MR Eisele, C Schlieker Proceedings of the National Academy of Sciences 110 (17), E1545-E1554, 2013 | 157 | 2013 |
Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes C Schlieker, WA Weihofen, E Frijns, LM Kattenhorn, R Gaudet, HL Ploegh Molecular cell 25 (5), 677-687, 2007 | 135 | 2007 |
Novel insights into the mechanism of chaperone-assisted protein disaggregation J Weibezahn, C Schlieker, P Tessarz, A Mogk, B Bukau Walter de Gruyter 386 (8), 739-744, 2005 | 134 | 2005 |
A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway CD Schlieker, AG Van der Veen, JR Damon, E Spooner, HL Ploegh Proceedings of the National Academy of Sciences 105 (47), 18255-18260, 2008 | 128 | 2008 |
Angiostatin formation involves disulfide bond reduction and proteolysis in kringle 5 of plasmin P Stathakis, AJ Lay, M Fitzgerald, C Schlieker, LJ Matthias, PJ Hogg Journal of Biological Chemistry 274 (13), 8910-8916, 1999 | 126 | 1999 |
Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier AG Van der Veen, K Schorpp, C Schlieker, L Buti, JR Damon, E Spooner, ... Proceedings of the National Academy of Sciences 108 (5), 1763-1770, 2011 | 119 | 2011 |
ClpV, a unique Hsp100/Clp member of pathogenic proteobacteria C Schlieker, H Zentgraf, P Dersch, A Mogk Walter de Gruyter 386 (11), 1115-1127, 2005 | 111 | 2005 |
Enzymatic blockade of the ubiquitin-proteasome pathway R Ernst, JHL Claessen, B Mueller, S Sanyal, E Spooner, AG van der Veen, ... PLoS biology 8 (3), e1000605, 2011 | 107 | 2011 |
Solubilization of aggregated proteins by ClpB/DnaK relies on the continuous extraction of unfolded polypeptides C Schlieker, I Tews, B Bukau, A Mogk FEBS letters 578 (3), 351-356, 2004 | 99 | 2004 |
The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations PL Tsai, C Zhao, E Turner, C Schlieker Elife 5, e16011, 2016 | 98 | 2016 |
The mechanism of Torsin ATPase activation RSH Brown, C Zhao, AR Chase, J Wang, C Schlieker Proceedings of the National Academy of Sciences 111 (45), E4822-E4831, 2014 | 89 | 2014 |