Ignacio Pérez de Castro
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Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression
MJ Bueno, IP de Castro, MG de Cedron, J Santos, GA Calin, JC Cigudosa, ...
Cancer cell 13 (6), 496-506, 2008
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
TG Bivona, SE Quatela, BO Bodemann, IM Ahearn, MJ Soskis, A Mor, ...
Molecular cell 21 (4), 481-493, 2006
Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1
TG Bivona, I Pérez de Castro, IM Ahearn, TM Grana, VK Chiu, PJ Lockyer, ...
Nature 424 (6949), 694-698, 2003
Control of cell proliferation pathways by microRNAs
MJ Bueno, IP de Castro, M Malumbres
Cell cycle 7 (20), 3143-3148, 2008
Psychiatric comorbidity in pathological gamblers seeking treatment
A Ibáñez, C Blanco, E Donahue, HR Lesieur, I Pérez de Castro, ...
American Journal of Psychiatry 158 (10), 1733-1735, 2001
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
I Pérez de Castro, G de Cárcer, M Malumbres
Carcinogenesis 28 (5), 899-912, 2007
Genetics of pathological gambling
A Ibáñez, C Blanco, I Perez de Castro, J Fernandez-Piqueras, J Sáiz-Ruiz
Journal of Gambling Studies 19, 11-22, 2003
Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene.
I Pérez de Castro, A Ibanez, P Torres, J Saiz-Ruiz, J Fernandez-Piqueras
Pharmacogenetics 7 (5), 345-348, 1997
Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15INK4b
M Malumbres, IP De Castro, MI Hernández, M Jiménez, T Corral, ...
Molecular and cellular biology, 2000
Systemic tumor targeting and killing by Sindbis viral vectors
JC Tseng, B Levin, A Hurtado, H Yee, IP De Castro, M Jimenez, ...
Nature biotechnology 22 (1), 70-77, 2004
Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus
I Perez de Castro, TG Bivona, MR Philips, A Pellicer
Molecular and cellular biology 24 (8), 3485-3496, 2004
Targeting cell cycle kinases for cancer therapy
G de Cárcer, I Perez de Castro, M Malumbres
Current medicinal chemistry 14 (9), 969-985, 2007
Pathological gambling and DNA polymorphic markers at MAO-A and MAO-B genes
A Ibanez, IP De Castro, J Fernandez-Piqueras, C Blanco, J Saiz-Ruiz
Molecular psychiatry 5 (1), 105-109, 2000
Tpx2 controls spindle integrity, genome stability, and tumor development
C Aguirre-Portolés, AW Bird, A Hyman, M Cañamero, I Pérez de Castro, ...
Cancer research 72 (6), 1518-1528, 2012
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development
G Fernández-Miranda, M Trakala, J Martín, B Escobar, A González, ...
Development 138 (13), 2661-2672, 2011
Aurora B overexpression causes aneuploidy and p21Cip1 repression during tumor development
A González-Loyola, G Fernández-Miranda, M Trakala, D Partida, ...
Molecular and cellular biology, 2015
Genetic contribution to pathological gambling: possible association between a functional DNA polymorphism at the serotonin transporter gene (5-HTT) and affected men
IP de Castro, A Ibánez, J Saiz-Ruiz, J Fernández-Piqueras
Pharmacogenetics and Genomics 9 (3), 397-400, 1999
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas
M Malumbres, IP de Castro, J Santos, B Meléndez, R Mangues, ...
Oncogene 14 (11), 1361-1370, 1997
Aurora kinase A inhibitors: promising agents in antitumoral therapy
M Malumbres, I Perez de Castro
Expert opinion on therapeutic targets 18 (12), 1377-1393, 2014
SUMOylation modulates the function of Aurora-B kinase
G Fernández-Miranda, IP de Castro, M Carmena, C Aguirre-Portolés, ...
Journal of cell science 123 (16), 2823-2833, 2010
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Articles 1–20