| Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells H Niwa, J Miyazaki, AG Smith Nature genetics 24 (4), 372-376, 2000 | 4659 | 2000 |
| Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ... Cell 95 (3), 379-391, 1998 | 4395 | 1998 |
| Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells I Chambers, D Colby, M Robertson, J Nichols, S Lee, S Tweedie, A Smith Cell 113 (5), 643-655, 2003 | 4387 | 2003 |
| The ground state of embryonic stem cell self-renewal QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ... nature 453 (7194), 519-523, 2008 | 3953 | 2008 |
| BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3 QL Ying, J Nichols, I Chambers, A Smith Cell 115 (3), 281-292, 2003 | 2755 | 2003 |
| Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides AG Smith, JK Heath, DD Donaldson, GG Wong, J Moreau, M Stahl, ... nature 336 (6200), 688-690, 1988 | 2578 | 1988 |
| Naive and primed pluripotent states J Nichols, A Smith Cell stem cell 4 (6), 487-492, 2009 | 2135 | 2009 |
| Changing potency by spontaneous fusion QL Ying, J Nichols, EP Evans, AG Smith Nature 416 (6880), 545-548, 2002 | 2119 | 2002 |
| Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 H Niwa, T Burdon, I Chambers, A Smith Genes & development 12 (13), 2048-2060, 1998 | 2027 | 1998 |
| Embryo-derived stem cells: of mice and men AG Smith Annual review of cell and developmental biology 17 (1), 435-462, 2001 | 1834 | 2001 |
| Nanog safeguards pluripotency and mediates germline development I Chambers, J Silva, D Colby, J Nichols, B Nijmeijer, M Robertson, ... Nature 450 (7173), 1230-1234, 2007 | 1809 | 2007 |
| Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture QL Ying, M Stavridis, D Griffiths, M Li, A Smith Nature biotechnology 21 (2), 183-186, 2003 | 1805 | 2003 |
| Altered immune responses in mice lacking inducible nitric oxide synthase X Wei, IG Charles, A Smith, J Ure, G Feng, F Huang, D Xu, W Mullers, ... Nature 375 (6530), 408-411, 1995 | 1628 | 1995 |
| Nanog is the gateway to the pluripotent ground state J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ... Cell 138 (4), 722-737, 2009 | 1268 | 2009 |
| Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens SM Pollard, K Yoshikawa, ID Clarke, D Danovi, S Stricker, R Russell, ... Cell stem cell 4 (6), 568-580, 2009 | 1172 | 2009 |
| Niche-independent symmetrical self-renewal of a mammalian tissue stem cell L Conti, SM Pollard, T Gorba, E Reitano, M Toselli, G Biella, Y Sun, ... PLoS biology 3 (9), e283, 2005 | 1085 | 2005 |
| Promotion of reprogramming to ground state pluripotency by signal inhibition J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith PLoS biology 6 (10), e253, 2008 | 1050 | 2008 |
| Resetting transcription factor control circuitry toward ground-state pluripotency in human Y Takashima, G Guo, R Loos, J Nichols, G Ficz, F Krueger, D Oxley, ... Cell 158 (6), 1254-1269, 2014 | 1013 | 2014 |
| Capture of authentic embryonic stem cells from rat blastocysts M Buehr, S Meek, K Blair, J Yang, J Ure, J Silva, R McLay, J Hall, QL Ying, ... Cell 135 (7), 1287-1298, 2008 | 971 | 2008 |
| The transcriptional and epigenomic foundations of ground state pluripotency H Marks, T Kalkan, R Menafra, S Denissov, K Jones, H Hofemeister, ... Cell 149 (3), 590-604, 2012 | 968 | 2012 |
