Graham Pavitt (GD Pavitt)
Graham Pavitt (GD Pavitt)
Faculty of Biology Medicine and Health, University of Manchester
Verified email at - Homepage
Cited by
Cited by
Global translational responses to oxidative stress impact upon multiple levels of protein synthesis
D Shenton, JB Smirnova, JN Selley, K Carroll, SJ Hubbard, GD Pavitt, ...
Journal of Biological Chemistry 281 (39), 29011-29021, 2006
Tight binding of the phosphorylated α subunit of initiation factor 2 (eIF2α) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition …
T Krishnamoorthy, GD Pavitt, FAN Zhang, TE Dever, AG Hinnebusch
Molecular and cellular biology 21 (15), 5018-5030, 2001
The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression
TA Owen-Hughes, GD Pavitt, DS Santos, JM Sidebotham, CSJ Hulton, ...
Cell 71 (2), 255-265, 1992
eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange
GD Pavitt, KVA Ramaiah, SR Kimball, AG Hinnebusch
Genes & development 12 (4), 514-526, 1998
Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria
CSJ Hulton, A Seirafi, JCD Hinton, JM Sidebotham, L Waddell, GD Pavitt, ...
Cell 63 (3), 631-642, 1990
Protein synthesis initiation in eukaryotic cells
WC Merrick, GD Pavitt
Cold Spring Harbor perspectives in biology 10 (12), a033092, 2018
Conserved bipartite motifs in yeast eIF5 and eIF2Bϵ, GTPase-activating and GDP–GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2
K Asano, T Krishnamoorthy, L Phan, GD Pavitt, AG Hinnebusch
The EMBO journal 18 (6), 1673-1688, 1999
Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence?
CF Higgins, JCD Hinton, CSJ Hulton, T Owen‐Hughes, GD Pavitt, ...
Molecular microbiology 4 (12), 2007-2012, 1990
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
P Falletta, L Sanchez-del-Campo, J Chauhan, M Effern, A Kenyon, ...
Genes & development 31 (1), 18-33, 2017
New insights into translational regulation in the endoplasmic reticulum unfolded protein response
GD Pavitt, D Ron
Cold Spring Harbor perspectives in biology 4 (6), a012278, 2012
eIF2B, a mediator of general and gene-specific translational control
GD Pavitt
Biochemical Society Transactions 33 (6), 1487-1492, 2005
Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2
GD Pavitt, W Yang, AG Hinnebusch
Molecular and cellular biology, 1997
Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae
TE Dever, TG Kinzy, GD Pavitt
Genetics 203 (1), 65-107, 2016
Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation
E Gomez, SS Mohammad, GD Pavitt
The EMBO journal 21 (19), 5292-5301, 2002
Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2α: role of the α-and δ-subunits of eIF2B
SR Kimball, JR Fabian, GD Pavitt, AG Hinnebusch, LS Jefferson
Journal of Biological Chemistry 273 (21), 12841-12845, 1998
eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
MD Jennings, GD Pavitt
Nature 465 (7296), 378-381, 2010
Expression and mutational analysis of the nucleoid‐associated protein H‐NS of Salmonella typhimurium
JCD Hinton, DS Santos, A Seirafi, CSJ Hulton, GD Pavitt, CF Higgins
Molecular microbiology 6 (16), 2327-2337, 1992
Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity
JP Richardson, SS Mohammad, GD Pavitt
Molecular and cellular biology 24 (6), 2352-2363, 2004
The structural basis of translational control by eIF2 phosphorylation
T Adomavicius, M Guaita, Y Zhou, MD Jennings, Z Latif, AM Roseman, ...
Nature communications 10 (1), 2136, 2019
Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways
JB Smirnova, JN Selley, F Sanchez-Cabo, K Carroll, AA Eddy, ...
Molecular and cellular biology 25 (21), 9340-9349, 2005
The system can't perform the operation now. Try again later.
Articles 1–20