Cyrille Botté
Cyrille Botté
ApicoLipid Group Head, CNRS Research Director, Institute for Advanced Biosciences CNRS UMR5309
Verified email at - Homepage
Cited by
Cited by
Phosphatidic acid-mediated signaling regulates microneme secretion in Toxoplasma
HE Bullen, Y Jia, Y Yamaryo-Botté, H Bisio, O Zhang, NK Jemelin, ...
Cell host & microbe 19 (3), 349-360, 2016
Lipid profile remodeling in response to nitrogen deprivation in the microalgae Chlorella sp.(Trebouxiophyceae) and Nannochloropsis sp.(Eustigmatophyceae)
GJO Martin, DRA Hill, ILD Olmstead, A Bergamin, MJ Shears, DA Dias, ...
PLoS One 9 (8), e103389, 2014
Evolution of galactoglycerolipid biosynthetic pathways–from cyanobacteria to primary plastids and from primary to secondary plastids
D Petroutsos, S Amiar, H Abida, LJ Dolch, O Bastien, F Rébeillé, J Jouhet, ...
Progress in lipid research 54, 68-85, 2014
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites
CY Botté, Y Yamaryo-Botté, TWT Rupasinghe, KA Mullin, JI MacRae, ...
Proceedings of the National Academy of Sciences 110 (18), 7506-7511, 2013
The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of action
C Biot, W Castro, CY Botté, M Navarro
Dalton Transactions 41 (21), 6335-6349, 2012
Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts
MJ Shears, CY Botté, GI McFadden
Molecular and biochemical parasitology 199 (1-2), 34-50, 2015
Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1
G Vanwalleghem, F Fontaine, L Lecordier, P Tebabi, K Klewe, DP Nolan, ...
Nature communications 6 (1), 8078, 2015
Plasmodium falciparum apicoplast drugs: targets or off-targets?
CY Botté, F Dubar, GI McFadden, E Maréchal, C Biot
Chemical reviews 112 (3), 1269-1283, 2012
Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana
CY Botté, M Deligny, A Roccia, AL Bonneau, N Saïdani, H Hardré, S Aci, ...
Nature chemical biology 7 (11), 834-842, 2011
Role of phosphatidic acid in plant galactolipid synthesis
E Dubots, C Botté, L Boudière, Y Yamaryo-Botté, J Jouhet, E Maréchal, ...
Biochimie 94 (1), 86-93, 2012
Lipidomic Analysis of Toxoplasma gondii Reveals Unusual Polar Lipids
R Welti, E Mui, A Sparks, S Wernimont, G Isaac, M Kirisits, M Roth, ...
Biochemistry 46 (48), 13882-13890, 2007
Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
AD Uboldi, ML Wilde, EA McRae, RJ Stewart, LF Dagley, L Yang, ...
PLoS biology 16 (9), e2005642, 2018
Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant …
S Amiar, JI MacRae, DL Callahan, D Dubois, GG van Dooren, MJ Shears, ...
PLoS pathogens 12 (8), e1005765, 2016
Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites
CY Botté, Y Yamaryo-Botté, J Janouškovec, T Rupasinghe, PJ Keeling, ...
Journal of Biological Chemistry 286 (34), 29893-29903, 2011
Molecular modeling and site-directed mutagenesis of plant chloroplast monogalactosyldiacylglycerol synthase reveal critical residues for activity
C Botté, C Jeanneau, L Snajdrova, O Bastien, A Imberty, C Breton, ...
Journal of Biological Chemistry 280 (41), 34691-34701, 2005
Galvestine-1, a novel chemical probe for the study of the glycerolipid homeostasis system in plant cells
L Boudière, CY Botté, N Saidani, M Lajoie, J Marion, L Brehelin, ...
Molecular BioSystems 8 (8), 2023-2035, 2012
Division and adaptation to host environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelle remodeling
S Amiar, NJ Katris, L Berry, S Dass, S Duley, CS Arnold, MJ Shears, ...
Cell Reports 30 (11), 3778-3792. e9, 2020
Enhanced antimalarial activity of novel synthetic aculeatin derivatives
M Peuchmaur, N Saïdani, C Botté, E Maréchal, H Vial, YS Wong
Journal of medicinal chemistry 51 (16), 4870-4873, 2008
An apically located hybrid guanylate cyclase–ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii
L Yang, AD Uboldi, S Seizova, ML Wilde, MJ Coffey, NJ Katris, ...
Journal of Biological Chemistry 294 (22), 8959-8972, 2019
The apicoplast: a key target to cure malaria
J I MacRae, E Maréchal, C Biot, C y Botté
Current pharmaceutical design 18 (24), 3490-3504, 2012
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