The BCL-2 protein family: opposing activities that mediate cell death RJ Youle, A Strasser Nature reviews Molecular cell biology 9 (1), 47-59, 2008 | 5770 | 2008 |
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy D Narendra, A Tanaka, DF Suen, RJ Youle The Journal of cell biology 183 (5), 795-803, 2008 | 4310 | 2008 |
Mitochondrial fission, fusion, and stress RJ Youle, AM Van Der Bliek Science 337 (6098), 1062-1065, 2012 | 3643 | 2012 |
Mechanisms of mitophagy RJ Youle, DP Narendra Nature reviews Molecular cell biology 12 (1), 9-14, 2011 | 3548 | 2011 |
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin DP Narendra, SM Jin, A Tanaka, DF Suen, CA Gautier, J Shen, ... PLoS biology 8 (1), e1000298, 2010 | 3094 | 2010 |
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ... Nature 524 (7565), 309-314, 2015 | 2514 | 2015 |
Movement of Bax from the cytosol to mitochondria during apoptosis KG Wolter, YT Hsu, CL Smith, A Nechushtan, XG Xi, RJ Youle The Journal of cell biology 139 (5), 1281-1292, 1997 | 2409 | 1997 |
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson’s disease AM Pickrell, RJ Youle Neuron 85 (2), 257-273, 2015 | 2278 | 2015 |
The role of mitochondria in apoptosis C Wang, RJ Youle Annual review of genetics 43 (1), 95-118, 2009 | 2200 | 2009 |
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis S Frank, B Gaume, ES Bergmann-Leitner, WW Leitner, EG Robert, ... Developmental cell 1 (4), 515-525, 2001 | 2089 | 2001 |
Mitophagy and quality control mechanisms in mitochondrial maintenance S Pickles, P Vigié, RJ Youle Current Biology 28 (4), R170-R185, 2018 | 1745 | 2018 |
Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics JC Martinou, RJ Youle Developmental cell 21 (1), 92-101, 2011 | 1694 | 2011 |
Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis YT Hsu, KG Wolter, RJ Youle Proceedings of the National Academy of Sciences 94 (8), 3668-3672, 1997 | 1570 | 1997 |
Mitochondrial dynamics and apoptosis DF Suen, KL Norris, RJ Youle Genes & development 22 (12), 1577-1590, 2008 | 1543 | 2008 |
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin A Tanaka, MM Cleland, S Xu, DP Narendra, DF Suen, M Karbowski, ... Journal of Cell Biology 191 (7), 1367-1380, 2010 | 1494 | 2010 |
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle Journal of Cell Biology 191 (5), 933-942, 2010 | 1433 | 2010 |
Structure of Bax: coregulation of dimer formation and intracellular localization M Suzuki, RJ Youle, N Tjandra Cell 103 (4), 645-654, 2000 | 1425 | 2000 |
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis Y Lee, SY Jeong, M Karbowski, CL Smith, RJ Youle Molecular biology of the cell 15 (11), 5001-5011, 2004 | 1321 | 2004 |
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity LA Kane, M Lazarou, AI Fogel, Y Li, K Yamano, SA Sarraf, S Banerjee, ... Journal of Cell Biology 205 (2), 143-153, 2014 | 1309 | 2014 |
The mitochondrial basis of aging N Sun, RJ Youle, T Finkel Molecular cell 61 (5), 654-666, 2016 | 1298 | 2016 |