Guillermo de Cárcer
Guillermo de Cárcer
Research Group Leader at the "Alberto Sols" Biomedical Research Institute (IIBM-CSIC)
Verified email at
Cited by
Cited by
From Plk1 to Plk5: functional evolution of polo-like kinases
G de Cárcer, G Manning, M Malumbres
Cell cycle 10 (14), 2255-2262, 2011
Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62
P Sanchez, G De Carcer, IV Sandoval, J Moscat, MT Diaz-Meco
Molecular and cellular biology 18 (5), 3069-3080, 1998
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
I Pérez de Castro, G de Cárcer, M Malumbres
Carcinogenesis 28 (5), 899-912, 2007
Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α, δ phosphatase
E Manchado, M Guillamot, G de Cárcer, M Eguren, M Trickey, ...
Cancer cell 18 (6), 641-654, 2010
HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
A Elorza, I Soro-Arnáiz, F Meléndez-Rodríguez, V Rodríguez-Vaello, ...
Molecular Cell, 2012
Targeting cell cycle kinases for cancer therapy
G de Cárcer, I Perez de Castro, M Malumbres
Current medicinal chemistry 14 (9), 969-985, 2007
Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin
IG Muñoz, H Yébenes, M Zhou, P Mesa, M Serna, AY Park, ...
Nature structural & molecular biology 18 (1), 14-19, 2011
Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression
G de Cárcer, B Escobar, AM Higuero, L García, A Ansón, G Pérez, ...
Molecular and cellular biology, 2011
Plk1 overexpression induces chromosomal instability and suppresses tumor development.
G de Cárcer, SV Venkateswaran, L Salgueiro, A El Bakkali, K Somogyi, ...
Nature communications. 9 (1), 3012, 2018
Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability
G De Cárcer, M do Carmo Avides, MJ Lallena, DM Glover, C González
The EMBO journal, 2001
Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization
B García-Álvarez, G de Cárcer, S Ibañez, E Bragado-Nilsson, G Montoya
Proceedings of the National Academy of Sciences 104 (9), 3107-3112, 2007
Aurora B overexpression causes aneuploidy and p21Cip1 repression during tumor development
A González-Loyola, G Fernández-Miranda, M Trakala, D Partida, ...
Molecular and cellular biology, 2015
TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis
P Munoz, R Blanco, G de Carcer, S Schoeftner, R Benetti, JM Flores, ...
Molecular and cellular biology 29 (6), 1608-1625, 2009
Protein 4.1 is a component of the nuclear matrix of mammalian cells
G De Cárcer, MJ Lallena, I Correas
Biochemical Journal 312 (3), 871-877, 1995
Low dose of amino-modified nanoparticles induces cell cycle arrest
JA Kim, C Åberg, G de Cárcer, M Malumbres, A Salvati, KA Dawson
ACS nano 7 (9), 7483-7494, 2013
Heat shock protein 90 regulates the metaphase-anaphase transition in a polo-like kinase-dependent manner
G de Cárcer
Cancer research 64 (15), 5106-5112, 2004
The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor?
G de Cárcer
Gene 10 (3), 208, 2019
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
IP de Castro, G de Carcer, G Montoya, M Malumbres
Current opinion in pharmacology 8 (4), 375-383, 2008
The functional organization of the nucleolus in proliferating plant cells
FJ Medina, A Cerdido, G Cárcer
PAGEPress, 2000
Simultaneous localization of transcription and early processing markers allows dissection of functional domains in the plant cell nucleolus
G de Cárcer, FJ Medina
Journal of structural biology 128 (2), 139-151, 1999
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