The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease A Kadioglu, JN Weiser, JC Paton, PW Andrew Nature Reviews Microbiology 6 (4), 288-301, 2008 | 1555 | 2008 |
Alternatives to antibiotics—a pipeline portfolio review L Czaplewski, R Bax, M Clokie, M Dawson, H Fairhead, VA Fischetti, ... The Lancet infectious diseases 16 (2), 239-251, 2016 | 947 | 2016 |
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4 EA McNeela, A Burke, DR Neill, C Baxter, VE Fernandes, D Ferreira, ... PLoS pathogens 6 (11), e1001191, 2010 | 426 | 2010 |
Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis MR Oggioni, C Trappetti, A Kadioglu, M Cassone, F Iannelli, S Ricci, ... Molecular microbiology 61 (5), 1196-1210, 2006 | 353 | 2006 |
The role of pneumolysin in pneumococcal pneumonia and meningitis RA Hirst, A Kadioglu, C O'callaghan, PW Andrew Clinical & Experimental Immunology 138 (2), 195-201, 2004 | 326 | 2004 |
Host cellular immune response to pneumococcal lung infection in mice A Kadioglu, NA Gingles, K Grattan, A Kerr, TJ Mitchell, PW Andrew Infection and immunity 68 (2), 492-501, 2000 | 287 | 2000 |
Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis S Manco, F Hernon, H Yesilkaya, JC Paton, PW Andrew, A Kadioglu Infection and immunity 74 (7), 4014-4020, 2006 | 261 | 2006 |
Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux M Karmakar, M Katsnelson, HA Malak, NG Greene, SJ Howell, AG Hise, ... The Journal of Immunology 194 (4), 1763-1775, 2015 | 251 | 2015 |
Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice BD Henry, DR Neill, KA Becker, S Gore, L Bricio-Moreno, R Ziobro, ... Nature biotechnology 33 (1), 81-88, 2015 | 244 | 2015 |
The innate immune response to pneumococcal lung infection: the untold story A Kadioglu, PW Andrew Trends in immunology 25 (3), 143-149, 2004 | 226 | 2004 |
Role of Manganese-Containing Superoxide Dismutase in Oxidative Stress and Virulence of Streptococcus pneumoniae H Yesilkaya, A Kadioglu, N Gingles, JE Alexander, TJ Mitchell, ... Infection and immunity 68 (5), 2819-2826, 2000 | 217 | 2000 |
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection YM Ali, NJ Lynch, KS Haleem, T Fujita, Y Endo, S Hansen, U Holmskov, ... PLoS pathogens 8 (7), e1002793, 2012 | 213 | 2012 |
Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa EM Waters, DR Neill, B Kaman, JS Sahota, MRJ Clokie, C Winstanley, ... Thorax 72 (7), 666-667, 2017 | 211 | 2017 |
Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults DM Ferreira, DR Neill, M Bangert, JF Gritzfeld, N Green, AKA Wright, ... American journal of respiratory and critical care medicine 187 (8), 855-864, 2013 | 206 | 2013 |
Sialic acid: a preventable signal for pneumococcal biofilm formation, colonization, and invasion of the host C Trappetti, A Kadioglu, M Carter, J Hayre, F Iannelli, G Pozzi, ... The Journal of infectious diseases 199 (10), 1497-1505, 2009 | 203 | 2009 |
Upper and Lower Respiratory Tract Infection by Streptococcus pneumoniae Is Affected by Pneumolysin Deficiency and Differences in Capsule Type A Kadioglu, S Taylor, F Iannelli, G Pozzi, TJ Mitchell, PW Andrew Infection and immunity 70 (6), 2886-2890, 2002 | 198 | 2002 |
CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection A Kadioglu, W Coward, MJ Colston, CRA Hewitt, PW Andrew Infection and immunity 72 (5), 2689-2697, 2004 | 193 | 2004 |
Protein Serine/Threonine Kinase StkP Positively Controls Virulence and Competence in Streptococcus pneumoniae J Echenique, A Kadioglu, S Romao, PW Andrew, MC Trombe Infection and immunity 72 (4), 2434-2437, 2004 | 175 | 2004 |
Role of genetic resistance in invasive pneumococcal infection: identification and study of susceptibility and resistance in inbred mouse strains NA Gingles, JE Alexander, A Kadioglu, PW Andrew, A Kerr, TJ Mitchell, ... Infection and immunity 69 (1), 426-434, 2001 | 169 | 2001 |
Capsule Type of Streptococcus pneumoniae Determines Growth Phenotype LJ Hathaway, SD Brugger, B Morand, M Bangert, JU Rotzetter, C Hauser, ... PLoS pathogens 8 (3), e1002574, 2012 | 153 | 2012 |