Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits SC Tang, TV Arumugam, X Xu, A Cheng, MR Mughal, DG Jo, JD Lathia, ... Proceedings of the National Academy of Sciences 104 (34), 13798-13803, 2007 | 927 | 2007 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. M Consortium, WKW Théry C Journal of Extracellular Vesicles 13 (2), 2024 | 770 | 2024 |
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke YW D Fann, SY Lee, S Manzanero, SC Tang, M Gelderblom, P Chunduri, ... Cell death & disease 4 (9), e790-e790, 2013 | 467 | 2013 |
Oxidative stress activates a positive feedback between the γ‐and β‐secretase cleavages of the β‐amyloid precursor protein E Tamagno, M Guglielmotto, M Aragno, R Borghi, R Autelli, L Giliberto, ... Journal of neurochemistry 104 (3), 683-695, 2008 | 427 | 2008 |
Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery T Thambi, VG Deepagan, HY Yoon, HS Han, SH Kim, S Son, DG Jo, ... Biomaterials 35 (5), 1735-1743, 2014 | 360 | 2014 |
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment L Weissman, DG Jo, MM Sørensen, NC de Souza-Pinto, WR Markesbery, ... Nucleic acids research 35 (16), 5545-5555, 2007 | 322 | 2007 |
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal SC Tang, JD Lathia, PK Selvaraj, DG Jo, MR Mughal, A Cheng, DA Siler, ... Experimental neurology 213 (1), 114-121, 2008 | 307 | 2008 |
Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke TV Arumugam, SL Chan, DG Jo, G Yilmaz, SC Tang, A Cheng, ... Nature medicine 12 (6), 621-623, 2006 | 304 | 2006 |
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging DH Hyun, SS Emerson, DG Jo, MP Mattson, R De Cabo Proceedings of the National Academy of Sciences 103 (52), 19908-19912, 2006 | 300 | 2006 |
Evidence that NF-κB and MAPK signaling promotes NLRP inflammasome activation in neurons following ischemic stroke DYW Fann, YA Lim, YL Cheng, KZ Lok, P Chunduri, SH Baik, ... Molecular neurobiology 55, 1082-1096, 2018 | 299 | 2018 |
Proapoptotic effects of tau cleavage product generated by caspase-3 CW Chung, YH Song, IK Kim, WJ Yoon, BR Ryu, DG Jo, HN Woo, ... Neurobiology of disease 8 (1), 162-172, 2001 | 274 | 2001 |
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death TV Arumugam, SC Tang, JD Lathia, A Cheng, MR Mughal, S Chigurupati, ... Proceedings of the National Academy of Sciences 104 (35), 14104-14109, 2007 | 266 | 2007 |
Inhibition of Drp1 ameliorates synaptic depression, Aβ deposition, and cognitive impairment in an Alzheimer's disease model SH Baek, SJ Park, JI Jeong, SH Kim, J Han, JW Kyung, SH Baik, Y Choi, ... Journal of Neuroscience 37 (20), 5099-5110, 2017 | 230 | 2017 |
Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration CH Woo, HK Kim, GY Jung, YJ Jung, KS Lee, YE Yun, J Han, J Lee, ... Journal of Extracellular Vesicles 9 (1), 1735249, 2020 | 213 | 2020 |
In situ diselenide-crosslinked polymeric micelles for ROS-mediated anticancer drug delivery VG Deepagan, S Kwon, DG You, W Um, H Ko, H Lee, DG Jo, YM Kang, ... Biomaterials 103, 56-66, 2016 | 188 | 2016 |
Essential role of E2-25K/Hip-2 in mediating amyloid-β neurotoxicity S Song, SY Kim, YM Hong, DG Jo, JY Lee, SM Shim, CW Chung, SJ Seo, ... Molecular cell 12 (3), 553-563, 2003 | 188 | 2003 |
Involvement of notch signaling in wound healing S Chigurupati, TV Arumugam, TG Son, JD Lathia, S Jameel, MR Mughal, ... PloS one 2 (11), e1167, 2007 | 183 | 2007 |
Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death MJ Kim, DG Jo, GS Hong, BJ Kim, M Lai, DH Cho, KW Kim, ... Proceedings of the National Academy of Sciences 99 (15), 9870-9875, 2002 | 183 | 2002 |
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models G Bahn, JS Park, UJ Yun, YJ Lee, Y Choi, JS Park, SH Baek, BY Choi, ... Proceedings of the National Academy of Sciences 116 (25), 12516-12523, 2019 | 179 | 2019 |
Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia Z Wei, S Chigurupati, TV Arumugam, DG Jo, H Li, SL Chan Stroke 42 (9), 2589-2594, 2011 | 170 | 2011 |