| Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling N Kayagaki, IB Stowe, BL Lee, K O’Rourke, K Anderson, S Warming, ... Nature 526 (7575), 666-671, 2015 | 3337 | 2015 |
| Lysosomal protease pathways to apoptosis: cleavage of Bid, not pro-caspases, is the most likely route V Stoka, B Turk, SL Schendel, TH Kim, T Cirman, SJ Snipas, LM Ellerby, ... Journal of Biological Chemistry 276 (5), 3149-3157, 2001 | 876 | 2001 |
| Target protease specificity of the viral serpin CrmA: analysis of five caspases Q Zhou, S Snipas, K Orth, M Muzio, VM Dixit, GS Salvesen Journal of Biological Chemistry 272 (12), 7797-7800, 1997 | 689 | 1997 |
| The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis P Mehlen, S Rabizadeh, SJ Snipas, N Assa-Munt, GS Salvesen, ... Nature 395 (6704), 801-804, 1998 | 550 | 1998 |
| Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... Science advances 6 (42), eabd4596, 2020 | 363 | 2020 |
| Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex Q Zhou, JF Krebs, SJ Snipas, A Price, ES Alnemri, KJ Tomaselli, ... Biochemistry 37 (30), 10757-10765, 1998 | 293 | 1998 |
| Caspase-14 is a novel developmentally regulated protease S Hu, SJ Snipas, C Vincenz, G Salvesen, VM Dixit Journal of Biological Chemistry 273 (45), 29648-29653, 1998 | 263 | 1998 |
| Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B. LT Quan, M Tewari, K O'Rourke, V Dixit, SJ Snipas, GG Poirier, C Ray, ... Proceedings of the National Academy of Sciences 93 (5), 1972-1976, 1996 | 240 | 1996 |
| Cathepsin G inhibition by Serpinb1 and Serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation SS Burgener, NGF Leborgne, SJ Snipas, GS Salvesen, PI Bird, ... Cell reports 27 (12), 3646-3656. e5, 2019 | 217 | 2019 |
| Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ... Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014 | 171 | 2014 |
| Structural and kinetic determinants of protease substrates JC Timmer, W Zhu, C Pop, T Regan, SJ Snipas, AM Eroshkin, SJ Riedl, ... Nature structural & molecular biology 16 (10), 1101-1108, 2009 | 150 | 2009 |
| Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... biorxiv, 2020.04. 29.068890, 2020 | 115 | 2020 |
| Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase YI Wu, HG Munshi, R Sen, SJ Snipas, GS Salvesen, R Fridman, MS Stack Journal of Biological Chemistry 279 (9), 8278-8289, 2004 | 114 | 2004 |
| Mechanism and specificity of the human paracaspase MALT1 J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ... Biochemical Journal 443 (1), 287-295, 2012 | 109 | 2012 |
| Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke N Akpan, E Serrano-Saiz, BE Zacharia, ML Otten, AF Ducruet, SJ Snipas, ... Journal of neuroscience 31 (24), 8894-8904, 2011 | 104 | 2011 |
| Activation and specificity of human caspase-10 K Wachmann, C Pop, BJ van Raam, M Drag, PD Mace, SJ Snipas, ... Biochemistry 49 (38), 8307-8315, 2010 | 104 | 2010 |
| Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 MLG Ramirez, M Poreba, SJ Snipas, K Groborz, M Drag, GS Salvesen Journal of Biological Chemistry 293 (18), 7058-7067, 2018 | 93 | 2018 |
| Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates M Poreba, P Kasperkiewicz, SJ Snipas, D Fasci, GS Salvesen, M Drag Cell Death & Differentiation 21 (9), 1482-1492, 2014 | 86 | 2014 |
| The mechanism of peptide-binding specificity of IAP BIR domains BP Eckelman, M Drag, SJ Snipas, GS Salvesen Cell Death & Differentiation 15 (5), 920-928, 2008 | 72 | 2008 |
| Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families M Poreba, A Szalek, W Rut, P Kasperkiewicz, I Rutkowska-Wlodarczyk, ... Scientific reports 7 (1), 1-13, 2017 | 71 | 2017 |
