Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B G Rena, S Guo, SC Cichy, TG Unterman, P Cohen Journal of Biological Chemistry 274 (24), 17179-17183, 1999 | 958 | 1999 |
Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models to disease mechanisms S Guo The Journal of endocrinology 220 (2), T1, 2014 | 935 | 2014 |
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter … S Guo, G Rena, S Cichy, X He, P Cohen, T Unterman Journal of Biological Chemistry 274 (24), 17184-17192, 1999 | 700 | 1999 |
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression W Zhang, S Patil, B Chauhan, S Guo, DR Powell, J Le, A Klotsas, ... Journal of Biological Chemistry 281 (15), 10105-10117, 2006 | 644 | 2006 |
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation XC Dong, KD Copps, S Guo, Y Li, R Kollipara, RA DePinho, MF White Cell metabolism 8 (1), 65-76, 2008 | 538 | 2008 |
Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the Forkhead transcription factor FKHR: evidence for insulin response unit-dependent and … D Schmoll, KS Walker, DR Alessi, R Grempler, A Burchell, S Guo, ... Journal of Biological Chemistry 275 (46), 36324-36333, 2000 | 447 | 2000 |
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms: direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding X Zhang, L Gan, H Pan, S Guo, X He, ST Olson, A Mesecar, S Adam, ... Journal of Biological Chemistry 277 (47), 45276-45284, 2002 | 383 | 2002 |
Foxo1 integrates insulin signaling with mitochondrial function in the liver Z Cheng, S Guo, K Copps, X Dong, R Kollipara, JT Rodgers, RA Depinho, ... Nature medicine 15 (11), 1307-1311, 2009 | 356 | 2009 |
Metformin improves mitochondrial respiratory activity through activation of AMPK Y Wang, H An, T Liu, C Qin, H Sesaki, S Guo, S Radovick, M Hussain, ... Cell reports 29 (6), 1511-1523. e5, 2019 | 339 | 2019 |
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting G Rena, AR Prescott, S Guo, P Cohen, TG Unterman Biochemical Journal 354 (3), 605-612, 2001 | 335 | 2001 |
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site YL Woods, G Rena, N Morrice, A Barthel, W Becker, S Guo, TG Unterman, ... Biochemical Journal 355 (3), 597-607, 2001 | 331 | 2001 |
Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells MR Abid, S Guo, T Minami, KC Spokes, K Ueki, C Skurk, K Walsh, ... Arteriosclerosis, thrombosis, and vascular biology 24 (2), 294-300, 2004 | 306 | 2004 |
Etiology of metabolic syndrome and dietary intervention H Xu, X Li, H Adams, K Kubena, S Guo International journal of molecular sciences 20 (1), 128, 2018 | 287 | 2018 |
Estrogen improves insulin sensitivity and suppresses gluconeogenesis via the transcription factor Foxo1 H Yan, W Yang, F Zhou, X Li, Q Pan, Z Shen, G Han, A Newell-Fugate, ... Diabetes 68 (2), 291-304, 2019 | 281 | 2019 |
Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance Y Qi, Z Xu, Q Zhu, C Thomas, R Kumar, H Feng, DE Dostal, MF White, ... Diabetes 62 (11), 3887-3900, 2013 | 212 | 2013 |
Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice K Zhang, L Li, Y Qi, X Zhu, B Gan, RA DePinho, T Averitt, S Guo Endocrinology 153 (2), 631-646, 2012 | 203 | 2012 |
Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence SB Cichy, S Uddin, A Danilkovich, S Guo, A Klippel, TG Unterman Journal of Biological Chemistry 273 (11), 6482-6487, 1998 | 203 | 1998 |
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR P Li, H Lee, S Guo, TG Unterman, G Jenster, W Bai Molecular and cellular biology 23 (1), 104-118, 2003 | 190 | 2003 |
The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis S Guo, KD Copps, X Dong, S Park, Z Cheng, A Pocai, L Rossetti, M Sajan, ... Molecular and cellular biology, 2009 | 170 | 2009 |
Plasma asprosin levels are associated with glucose metabolism, lipid, and sex hormone profiles in females with metabolic‐related diseases X Li, M Liao, R Shen, L Zhang, H Hu, J Wu, X Wang, H Qu, S Guo, M Long, ... Mediators of inflammation 2018 (1), 7375294, 2018 | 160 | 2018 |