| Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer M Kraus, MB Alimzhanov, N Rajewsky, K Rajewsky Cell 117 (6), 787-800, 2004 | 745 | 2004 |
| B cell receptor signal strength determines B cell fate S Casola, KL Otipoby, M Alimzhanov, S Humme, N Uyttersprot, JL Kutok, ... Nature immunology 5 (3), 317-327, 2004 | 703 | 2004 |
| The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors M Hedvat, D Huszar, A Herrmann, JM Gozgit, A Schroeder, A Sheehy, ... Cancer cell 16 (6), 487-497, 2009 | 608 | 2009 |
| Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice MB Alimzhanov, DV Kuprash, MH Kosco-Vilbois, A Luz, RL Turetskaya, ... Proceedings of the National Academy of Sciences 94 (17), 9302-9307, 1997 | 463 | 1997 |
| Identification and characterization of MEDI4736, an antagonistic anti–PD-L1 monoclonal antibody R Stewart, M Morrow, SA Hammond, K Mulgrew, D Marcus, E Poon, ... Cancer immunology research 3 (9), 1052-1062, 2015 | 412 | 2015 |
| Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells R Endres, MB Alimzhanov, T Plitz, A Fütterer, MH Kosco-Vilbois, ... The Journal of experimental medicine 189 (1), 159-168, 1999 | 383 | 1999 |
| Targeted binding agents against B7-H1 C Queva, M Morrow, S Hammond, M Alimzhanov, J Babcook, IN Foltz, ... US Patent 8,779,108, 2014 | 331 | 2014 |
| B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity LI Pao, KP Lam, JM Henderson, JL Kutok, M Alimzhanov, L Nitschke, ... Immunity 27 (1), 35-48, 2007 | 316 | 2007 |
| FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses P Victoratos, J Lagnel, S Tzima, MB Alimzhanov, K Rajewsky, ... Immunity 24 (1), 65-77, 2006 | 147 | 2006 |
| Discovery of 5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak … S Ioannidis, ML Lamb, T Wang, L Almeida, MH Block, AM Davies, B Peng, ... Journal of medicinal chemistry 54 (1), 262-276, 2011 | 137 | 2011 |
| TNF and lymphotoxin β cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes DV Kuprash23, MB Alimzhanov, AV Tumanov, AO Anderson, K Pfeffer, ... The Journal of Immunology 163 (12), 6575-6580, 1999 | 102 | 1999 |
| Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching JH Wang, FW Alt, M Gostissa, A Datta, M Murphy, MB Alimzhanov, ... The Journal of experimental medicine 205 (13), 3079-3090, 2008 | 84 | 2008 |
| Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice DV Kuprash, MB Alimzhanov, AV Tumanov, SI Grivennikov, AN Shakhov, ... Molecular and cellular biology, 2002 | 81 | 2002 |
| Cloning and expression analysis of the murine lymphotoxin beta gene. DK Pokholok, IG Maroulakou, DV Kuprash, MB Alimzhanov, SV Kozlov, ... Proceedings of the National Academy of Sciences 92 (3), 674-678, 1995 | 63 | 1995 |
| Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors Q Su, S Ioannidis, C Chuaqui, L Almeida, M Alimzhanov, G Bebernitz, ... Journal of medicinal chemistry 57 (1), 144-158, 2014 | 60 | 2014 |
| Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo JE Dowling, M Alimzhanov, L Bao, C Chuaqui, CR Denz, E Jenkins, ... ACS Medicinal Chemistry Letters 7 (3), 300-305, 2016 | 56 | 2016 |
| Targeted binding agents against B7-H1 C Queva, M Morrow, S Hammond, M Alimzhanov, J Babcock, IN Foltz, ... US Patent 9,493,565, 2016 | 55 | 2016 |
| Structure and property based design of pyrazolo [1, 5-a] pyrimidine inhibitors of CK2 kinase with activity in vivo JE Dowling, M Alimzhanov, L Bao, MH Block, C Chuaqui, EL Cooke, ... ACS medicinal chemistry letters 4 (8), 800-805, 2013 | 50 | 2013 |
| Complement C 4 maintains peripheral B‐cell tolerance in a myeloid cell dependent manner P Chatterjee, AF Agyemang, MB Alimzhanov, S Degn, SA Tsiftsoglou, ... European journal of immunology 43 (9), 2441-2450, 2013 | 49 | 2013 |
| Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation. DV Kuprash, OA Osipovich, DK Pokholok, MB Alimzhanov, A Biragyn, ... Journal of immunology (Baltimore, Md.: 1950) 156 (7), 2465-2472, 1996 | 48 | 1996 |
Michelle L LambAstraZenecaVerified email at astrazeneca.com
