Chair, Department of Biochemistry and Molecular Pharmacology, Ellen and Gerald Ritter Professor of
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
M Pagano, SW Tam, AM Theodoras, P Beer-Romero, G Del Sal, V Chau, ...
Science 269 (5224), 682-685, 1995
Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
V Baldin, J Lukas, MJ Marcote, M Pagano, G Draetta
Genes & development 7 (5), 812-821, 1993
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
AC Carrano, E Eytan, A Hershko, M Pagano
Nature cell biology 1 (4), 193-199, 1999
Cyclin A is required at two points in the human cell cycle.
M Pagano, R Pepperkok, F Verde, W Ansorge, G Draetta
The EMBO journal 11 (3), 961-971, 1992
Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ...
Nature 416 (6882), 703-709, 2002
Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase Transition
M Ohtsubo, AM Theodoras, J Schumacher, JM Roberts, M Pagano
Molecular and cellular biology 15 (5), 2612-2624, 1995
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
M Loda, B Cukor, SW Tam, P Lavin, M Fiorentinc, GF Draetta, JM Jessup, ...
Nature medicine 3 (2), 231-234, 1997
The SCF ubiquitin ligase: insights into a molecular machine
T Cardozo, M Pagano
Nature reviews Molecular cell biology 5 (9), 739-751, 2004
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer
D Frescas, M Pagano
Nature Reviews Cancer 8 (6), 438-449, 2008
Regulation of the cdk inhibitor p27 and its deregulation in cancer
J Slingerland, M Pagano
Journal of cellular physiology 183 (1), 10-17, 2000
The F-box protein family
ET Kipreos, M Pagano
Genome biology 1, 1-7, 2000
S6K1-and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
NV Dorrello, A Peschiaroli, D Guardavaccaro, NH Colburn, NE Sherman, ...
Science 314 (5798), 467-471, 2006
Systematic analysis and nomenclature of mammalian F-box proteins
J Jin, T Cardozo, RC Lovering, SJ Elledge, M Pagano, JW Harper
Genes & development 18 (21), 2573-2580, 2004
Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex
BA Schulman, AC Carrano, PD Jeffrey, Z Bowen, ERE Kinnucan, ...
Nature 408 (6810), 381-386, 2000
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
A Montagnoli, F Fiore, E Eytan, AC Carrano, GF Draetta, A Hershko, ...
Genes & development 13 (9), 1181-1189, 1999
Mechanisms and function of substrate recruitment by F-box proteins
JR Skaar, JK Pagan, M Pagano
Nature reviews Molecular cell biology 14 (6), 369-381, 2013
Control of the SCFSkp2–Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase
T Bashir, NV Dorrello, V Amador, D Guardavaccaro, M Pagano
Nature 428 (6979), 190-193, 2004
The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27
D Ganoth, G Bornstein, TK Ko, B Larsen, M Tyers, M Pagano, A Hershko
Nature cell biology 3 (3), 321-324, 2001
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
V Esposito, A Baldi, A De Luca, AM Groger, M Loda, GG Giordano, ...
Cancer research 57 (16), 3381-3385, 1997
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