Marcel van Vugt
Marcel van Vugt
Professor of Molecular Oncology, University of Groningen, University Medical Centre
Verified email at - Homepage
Cited by
Cited by
Systematic discovery of in vivo phosphorylation networks
R Linding, LJ Jensen, GJ Ostheimer, MATM van Vugt, C Jųrgensen, ...
Cell 129 (7), 1415-1426, 2007
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
MATM Van Vugt, A Brįs, RH Medema
Molecular cell 15 (5), 799-811, 2004
Gene expression analysis identifies global gene dosage sensitivity in cancer
RSN Fehrmann, JM Karjalainen, M Krajewska, HJ Westra, D Maloney, ...
Nature genetics 47 (2), 115-125, 2015
Relevance of tumor-infiltrating immune cell composition and functionality for disease outcome in breast cancer
RD Bense, C Sotiriou, MJ Piccart-Gebhart, JBAG Haanen, ...
Journal of the National Cancer Institute 109 (1), djw192, 2017
Rectal and colon cancer: Not just a different anatomic site
K Tamas, AME Walenkamp, EGE De Vries, M Van Vugt, RG Beets-Tan, ...
Cancer treatment reviews 41 (8), 671-679, 2015
Getting in and out of mitosis with Polo-like kinase-1
MATM van Vugt, RH Medema
Oncogene 24 (17), 2844-2859, 2005
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint
MATM van Vugt, AK Gardino, R Linding, GJ Ostheimer, HC Reinhardt, ...
PLoS biology 8 (1), e1000287, 2010
14-3-3σ controls mitotic translation to facilitate cytokinesis
EW Wilker, MATM Van Vugt, SC Artim, PH Huang, CP Petersen, ...
Nature 446 (7133), 329-332, 2007
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization
HC Reinhardt, P Hasskamp, I Schmedding, S Morandell, MATM van Vugt, ...
Molecular cell 40 (1), 34-49, 2010
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery
I Mamely, MATM van Vugt, VAJ Smits, JI Semple, B Lemmens, A Perrakis, ...
Current Biology 16 (19), 1950-1955, 2006
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis
MATM Van Vugt, BCM Van De Weerdt, G Vader, H Janssen, J Calafat, ...
Journal of Biological Chemistry 279 (35), 36841-36854, 2004
Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM-or ATR-dependent fashion
MATM van Vugt, VAJ Smits, R Klompmaker, RH Medema
Journal of Biological Chemistry 276 (45), 41656-41660, 2001
cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers
C Hong, M Schubert, AE Tijhuis, M Requesens, M Roorda, ...
Nature 607 (7918), 366-373, 2022
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling
T van Harn, F Foijer, M van Vugt, R Banerjee, F Yang, A Oostra, H Joenje, ...
Genes & development 24 (13), 1377-1388, 2010
Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination
M Krajewska, AM Heijink, Y Bisselink, RI Seinstra, HHW Sillje, ...
Oncogene 32 (24), 3001-3008, 2013
The DNA damage response during mitosis
AM Heijink, M Krajewska, MATM van Vugt
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 750 (1 …, 2013
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
AM Heijink, F Talens, LT Jae, SE van Gijn, RSN Fehrmann, ...
Nature communications 10 (1), 100, 2019
ATR inhibition preferentially targets homologous recombination-deficient tumor cells
M Krajewska, RSN Fehrmann, PM Schoonen, S Labib, EGE De Vries, ...
Oncogene 34 (26), 3474-3481, 2015
Functional dynamics of Polo-like kinase 1 at the centrosome
K Kishi, MATM Van Vugt, K Okamoto, Y Hayashi, MB Yaffe
Molecular and cellular biology 29 (11), 3134-3150, 2009
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