Genomic DNA methylation: the mark and its mediators RJ Klose, AP Bird Trends in biochemical sciences 31 (2), 89-97, 2006 | 3158 | 2006 |
JmjC-domain-containing proteins and histone demethylation RJ Klose, EM Kallin, Y Zhang Nature reviews genetics 7 (9), 715-727, 2006 | 1475 | 2006 |
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ... EMBO reports 12 (5), 463-469, 2011 | 1155 | 2011 |
Regulation of histone methylation by demethylimination and demethylation RJ Klose, Y Zhang Nature reviews Molecular cell biology 8 (4), 307-318, 2007 | 1065 | 2007 |
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36 RJ Klose, K Yamane, Y Bae, D Zhang, H Erdjument-Bromage, P Tempst, ... Nature 442 (7100), 312-316, 2006 | 790 | 2006 |
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation NP Blackledge, AM Farcas, T Kondo, HW King, JF McGouran, ... Cell 157 (6), 1445-1459, 2014 | 786 | 2014 |
Understanding the relationship between DNA methylation and histone lysine methylation NR Rose, RJ Klose Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (12 …, 2014 | 662 | 2014 |
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation K Yamane, K Tateishi, RJ Klose, J Fang, LA Fabrizio, ... Molecular cell 25 (6), 801-812, 2007 | 597 | 2007 |
The retinoblastoma binding protein RBP2 is an H3K4 demethylase RJ Klose, Q Yan, Z Tothova, K Yamane, H Erdjument-Bromage, P Tempst, ... Cell 128 (5), 889-900, 2007 | 508 | 2007 |
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands AM Farcas, NP Blackledge, I Sudbery, HK Long, JF McGouran, NR Rose, ... elife 1, e00205, 2012 | 504 | 2012 |
DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG RJ Klose, SA Sarraf, L Schmiedeberg, SM McDermott, I Stancheva, ... Molecular cell 19 (5), 667-678, 2005 | 444 | 2005 |
Targeting Polycomb systems to regulate gene expression: modifications to a complex story NP Blackledge, NR Rose, RJ Klose Nature reviews Molecular cell biology 16 (11), 643-649, 2015 | 397 | 2015 |
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment S Cooper, M Dienstbier, R Hassan, L Schermelleh, J Sharif, ... Cell reports 7 (5), 1456-1470, 2014 | 365 | 2014 |
CpG islands recruit a histone H3 lysine 36 demethylase NP Blackledge, JC Zhou, MY Tolstorukov, AM Farcas, PJ Park, RJ Klose Molecular cell 38 (2), 179-190, 2010 | 359 | 2010 |
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ... Nature cell biology 12 (6), 618-624, 2010 | 349 | 2010 |
MeCP2 binding to DNA depends upon hydration at methyl-CpG KL Ho, IW McNae, L Schmiedeberg, RJ Klose, AP Bird, MD Walkinshaw Molecular cell 29 (4), 525-531, 2008 | 307 | 2008 |
Dynamic protein methylation in chromatin biology SS Ng, WW Yue, U Oppermann, RJ Klose Cellular and molecular life sciences 66, 407-422, 2009 | 293 | 2009 |
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection HK Long, NP Blackledge, RJ Klose Biochemical Society Transactions 41 (3), 727-740, 2013 | 289 | 2013 |
The molecular principles of gene regulation by Polycomb repressive complexes NP Blackledge, RJ Klose Nature reviews Molecular cell biology 22 (12), 815-833, 2021 | 281 | 2021 |
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function J Tao, K Hu, Q Chang, H Wu, NE Sherman, K Martinowich, RJ Klose, ... Proceedings of the National Academy of Sciences 106 (12), 4882-4887, 2009 | 270 | 2009 |