HSP90 at the hub of protein homeostasis: emerging mechanistic insights M Taipale, DF Jarosz, S Lindquist Nature reviews Molecular cell biology 11 (7), 515-528, 2010 | 2017 | 2010 |
Prions are a common mechanism for phenotypic inheritance in wild yeasts R Halfmann, DF Jarosz, SK Jones, A Chang, AK Lancaster, S Lindquist Nature 482 (7385), 363-368, 2012 | 466 | 2012 |
Hsp90 and environmental stress transform the adaptive value of natural genetic variation DF Jarosz, S Lindquist Science 330 (6012), 1820-1824, 2010 | 405 | 2010 |
Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish N Rohner, DF Jarosz, JE Kowalko, M Yoshizawa, WR Jeffery, ... Science 342 (6164), 1372-1375, 2013 | 385 | 2013 |
A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates DF Jarosz, VG Godoy, JC Delaney, JM Essigmann, GC Walker Nature 439 (7073), 225-228, 2006 | 288 | 2006 |
Intrinsically disordered proteins drive emergence and inheritance of biological traits S Chakrabortee, JS Byers, S Jones, DM Garcia, B Bhullar, A Chang, ... Cell 167 (2), 369-381. e12, 2016 | 208 | 2016 |
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms DF Jarosz, M Taipale, S Lindquist Annual review of genetics 44 (1), 189-216, 2010 | 195 | 2010 |
Cross-kingdom chemical communication drives a heritable, mutually beneficial prion-based transformation of metabolism DF Jarosz, JCS Brown, GA Walker, MS Datta, WL Ung, AK Lancaster, ... Cell 158 (5), 1083-1093, 2014 | 185 | 2014 |
Y-family DNA polymerases in Escherichia coli DF Jarosz, PJ Beuning, SE Cohen, GC Walker Trends in microbiology 15 (2), 70-77, 2007 | 180 | 2007 |
Protein-based inheritance: epigenetics beyond the chromosome ZH Harvey, Y Chen, DF Jarosz Molecular cell 69 (2), 195-202, 2018 | 177 | 2018 |
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB VG Godoy, DF Jarosz, SM Simon, A Abyzov, V Ilyin, GC Walker Molecular cell 28 (6), 1058-1070, 2007 | 124 | 2007 |
An evolutionarily conserved prion-like element converts wild fungi from metabolic specialists to generalists DF Jarosz, AK Lancaster, JCS Brown, S Lindquist Cell 158 (5), 1072-1082, 2014 | 121 | 2014 |
Y‐family DNA polymerases respond to DNA damage‐independent inhibition of replication fork progression VG Godoy, DF Jarosz, FL Walker, LA Simmons, GC Walker The EMBO journal 25 (4), 868-879, 2006 | 99 | 2006 |
It’s not magic–Hsp90 and its effects on genetic and epigenetic variation RA Zabinsky, GA Mason, C Queitsch, DF Jarosz Seminars in cell & developmental biology 88, 21-35, 2019 | 94 | 2019 |
A non-amyloid prion particle that activates a heritable gene expression program AK Chakravarty, T Smejkal, AK Itakura, DM Garcia, DF Jarosz Molecular cell 77 (2), 251-265. e9, 2020 | 93 | 2020 |
Mapping causal variants with single-nucleotide resolution reveals biochemical drivers of phenotypic change R She, DF Jarosz Cell 172 (3), 478-490. e15, 2018 | 77 | 2018 |
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo WL Neeley, S Delaney, YO Alekseyev, DF Jarosz, JC Delaney, ... Journal of Biological Chemistry 282 (17), 12741-12748, 2007 | 76 | 2007 |
Comprehensive and quantitative mapping of RNA–protein interactions across a transcribed eukaryotic genome R She, AK Chakravarty, CJ Layton, LM Chircus, JOL Andreasson, ... Proceedings of the National Academy of Sciences 114 (14), 3619-3624, 2017 | 75 | 2017 |
A prion epigenetic switch establishes an active chromatin state ZH Harvey, AK Chakravarty, RA Futia, DF Jarosz Cell 180 (5), 928-940. e14, 2020 | 72 | 2020 |
A common bacterial metabolite elicits prion-based bypass of glucose repression DM Garcia, D Dietrich, J Clardy, DF Jarosz Elife 5, e17978, 2016 | 58 | 2016 |