Stephen Holman
Stephen Holman
Associate Principal Scientist, AstraZeneca
Verified email at
Cited by
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The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics
F Lanucara, SW Holman, CJ Gray, CE Eyers
Nature Chemistry 6 (4), 281-294, 2014
Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy
P Brownridge, SW Holman, SJ Gaskell, CM Grant, VM Harman, ...
Proteomics 11 (15), 2957-2970, 2011
The use of selected reaction monitoring in quantitative proteomics
SW Holman, PFG Sims, CE Eyers
Bioanalysis 4 (14), 1763-1786, 2012
Direct and absolute quantification of over 1800 yeast proteins via selected reaction monitoring
C Lawless, SW Holman, P Brownridge, K Lanthaler, VM Harman, ...
Molecular & Cellular Proteomics 15 (4), 1309-1322, 2016
Analysis of intrinsic peptide detectability via integrated label-free and SRM-based absolute quantitative proteomics
AF Jarnuczak, DCH Lee, C Lawless, SW Holman, CE Eyers, SJ Hubbard
Journal of proteome research 15 (9), 2945-2959, 2016
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies
IE Elsemman, A Rodriguez Prado, P Grigaitis, M Garcia Albornoz, ...
Nature communications 13 (1), 801, 2022
Quantitative analysis of chaperone network throughput in budding yeast
P Brownridge, C Lawless, AB Payapilly, K Lanthaler, SW Holman, ...
Proteomics 13 (8), 1276-1291, 2013
Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription
F Lanucara, C Lam, J Mann, TP Monie, SAP Colombo, SW Holman, ...
Open biology 6 (7), 160055, 2016
Absolute protein quantification of the yeast chaperome under conditions of heat shock
RJ Mackenzie, C Lawless, SW Holman, K Lanthaler, RJ Beynon, ...
Proteomics 16 (15-16), 2128-2140, 2016
Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vaccine …
LX Neves, RA Wilson, P Brownridge, VM Harman, SW Holman, ...
Journal of proteome research 19 (1), 314-326, 2019
RePLiCal: a QconCAT protein for retention time standardization in proteomics studies
SW Holman, L McLean, CE Eyers
Journal of proteome research 15 (3), 1090-1102, 2016
Evaluation of dimethyl sulfoxide (DMSO) as a mobile phase additive during top 3 label-free quantitative proteomics
D Strzelecka, SW Holman, CE Eyers
International journal of mass spectrometry 391, 157-160, 2015
Advances in high‐resolution mass spectrometry applied to pharmaceuticals in 2020: A whole new age of information
C Géhin, SW Holman
Analytical Science Advances 2 (3-4), 142-156, 2021
High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 1. Evidence for an ortho effect on the fragmentation of 4 …
SW Holman, P Wright, GJ Langley
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2008
Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1
R Szatkowska, M Garcia-Albornoz, K Roszkowska, SW Holman, ...
Biochemical Journal 476 (7), 1053-1082, 2019
Peptide Scrambling During Collision-Induced Dissociation is Influenced by N-terminal Residue Basicity
R Chawner, SW Holman, SJ Gaskell, CE Eyers
Journal of the American Society for Mass Spectrometry 25 (11), 1927-1938, 2014
DOSCATs: Double standards for protein quantification
RJ Bennett, DM Simpson, SW Holman, S Ryan, P Brownridge, CE Eyers, ...
Scientific Reports 7 (1), 45570, 2017
A quantitative assessment of the chemical variation in food grade polyethylene cling film, a common wrapping material for illicit drugs, using attenuated total reflection …
SW Holman, TF Emmett, MD Cole
Analytical Methods 4 (6), 1667-1673, 2012
Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS)
SW Holman, DE Hammond, DM Simpson, J Waters, JL Hurst, RJ Beynon
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016
High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 2. An example of how unexpected dissociation behaviour could preclude …
SW Holman, P Wright, GJ Langley
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009
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