| Mitochondrial dysfunction in Huntington’s disease C Carmo, L Naia, C Lopes, AC Rego Polyglutamine disorders, 59-83, 2018 | 182 | 2018 |
| Comparative mitochondrial-based protective effects of resveratrol and nicotinamide in Huntington’s disease models L Naia, TR Rosenstock, AM Oliveira, SI Oliveira-Sousa, GL Caldeira, ... Molecular neurobiology 54 (7), 5385-5399, 2017 | 133 | 2017 |
| The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes V Lemos, RM De Oliveira, L Naia, É Szegö, E Ramos, S Pinho, F Magro, ... Human molecular genetics 26 (21), 4105-4117, 2017 | 92 | 2017 |
| Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington’s Disease human lymphoblasts L Naia, IL Ferreira, T Cunha-Oliveira, AI Duarte, M Ribeiro, ... Molecular neurobiology 51, 331-348, 2015 | 82 | 2015 |
| Histone deacetylase inhibitors protect against pyruvate dehydrogenase dysfunction in Huntington's disease L Naia, T Cunha-Oliveira, J Rodrigues, TR Rosenstock, A Oliveira, ... Journal of Neuroscience 37 (10), 2776-2794, 2017 | 62 | 2017 |
| Sirtuins: double players in Huntington's disease L Naia, AC Rego Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (10 …, 2015 | 62 | 2015 |
| Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics L Naia, C Carmo, S Campesan, L Fão, VE Cotton, J Valero, C Lopes, ... Free Radical Biology and Medicine 163, 163-179, 2021 | 60 | 2021 |
| Amyloid Β-peptide increases mitochondria-endoplasmic reticulum contact altering mitochondrial function and autophagosome formation in Alzheimer’s disease-related models NS Leal, G Dentoni, B Schreiner, L Naia, A Piras, C Graff, A Cattaneo, ... Cells 9 (12), 2552, 2020 | 54 | 2020 |
| Mitochondrial Ca2+ handling in Huntington's and Alzheimer's diseases–Role of ER-mitochondria crosstalk L Naia, IL Ferreira, E Ferreiro, AC Rego Biochemical and biophysical research communications 483 (4), 1069-1077, 2017 | 47 | 2017 |
| The sigma-1 receptor mediates pridopidine rescue of mitochondrial function in Huntington disease models L Naia, P Ly, SI Mota, C Lopes, C Maranga, P Coelho, N Gershoni-Emek, ... Neurotherapeutics 18, 1017-1038, 2021 | 42 | 2021 |
| Oxidizing effects of exogenous stressors in Huntington’s disease knock-in striatal cells—protective effect of cystamine and creatine M Ribeiro, AC Silva, J Rodrigues, L Naia, AC Rego toxicological sciences 136 (2), 487-499, 2013 | 42 | 2013 |
| Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin L Naia, M Ribeiro, J Rodrigues, AI Duarte, C Lopes, TR Rosenstock, ... Neuropeptides 58, 73-81, 2016 | 39 | 2016 |
| Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism M Zyśk, C Beretta, L Naia, A Dakhel, L Påvénius, H Brismar, M Lindskog, ... Journal of Neuroinflammation 20 (1), 43, 2023 | 35 | 2023 |
| Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models L Naia, M Shimozawa, E Bereczki, X Li, J Liu, R Jiang, R Giraud, NS Leal, ... Molecular psychiatry 28 (9), 3966-3981, 2023 | 33 | 2023 |
| Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling L Naia, CM Pinho, G Dentoni, J Liu, NS Leal, DMS Ferreira, B Schreiner, ... BMC biology 19, 1-21, 2021 | 32 | 2021 |
| Overexpression of BDNF and full-length trkb receptor ameliorate striatal neural survival in huntington's disease A Silva, L Naia, A Dominguez, M Ribeiro, J Rodrigues, OV Vieira, ... Neurodegenerative Diseases 15 (4), 207-218, 2015 | 32 | 2015 |
| Limited effect of chronic valproic acid treatment in a mouse model of Machado-Joseph disease S Esteves, S Duarte-Silva, L Naia, A Neves-Carvalho, A Teixeira-Castro, ... PLoS One 10 (10), e0141610, 2015 | 29 | 2015 |
| Mitochondrial and metabolic-based protective strategies in Huntington’s disease: the case of creatine and coenzyme Q L Naia, MJ Ribeiro, AC Rego Walter de Gruyter 23 (1), 13-28, 2012 | 27 | 2012 |
| Assessing mitochondrial function in in vitro and ex vivo models of Huntington’s disease IL Ferreira, C Carmo, L Naia, S I Mota, A Cristina Rego Huntington’s Disease, 415-442, 2018 | 26 | 2018 |
| The potential of small molecules to modulate the mitochondria–endoplasmic reticulum interplay in Alzheimer’s disease G Dentoni, L Castro-Aldrete, L Naia, M Ankarcrona Frontiers in Cell and Developmental Biology 10, 920228, 2022 | 11 | 2022 |
Tatiana RosenstockPrincipal Scientist, In vitro Neuroscience, Sygnature Discovery, UKVerified email at sygnaturediscovery.com
