Pieter R Cullis

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Bally MBC CancerVerified email at bccrc.ca
Yuen Yi C. TamIntegrated Nanotherapeutics Inc.Verified email at mail.ubc.ca
Ismail HafezUniversity of British ColumbiaVerified email at mail.ubc.ca
Theresa M AllenUniversity of AlbertaVerified email at ualberta.ca
Nathan M BelliveauPostdoctoral Associate, Howard Hughes Medical Institute, University of WashingtonVerified email at uw.edu
Sol M. GrunerThe John L. Wetherill Professor of Physics Emeritus, Cornell UniversityVerified email at cornell.edu
Dana V DevineUniversity of British Columbia; Canadian Blood ServicesVerified email at pathology.ubc.ca
Justin Barry LeePhD in Biochemistry & Molecular BiologyVerified email at interchange.ubc.ca
D. Peter TielemanCanada Research Chair in Molecular Simulation, University of CalgaryVerified email at ucalgary.ca
Ravi L RungtaUniversité de MontréalVerified email at umontreal.ca
Brian MacVicarProfessor, University of British ColumbiaVerified email at brain.ubc.ca
Katarina EdwardsProfessor in Physical Chemistry, Uppsala UniversityVerified email at kemi.uu.se
Ajoy C ChakrabartiBill & Melinda Gates FoundationVerified email at cornell.edu
Sam G. Raney, PhDU.S. Food & Drug AdministrationVerified email at aya.yale.edu
EDWARD SARAVOLACDIATRANZ OTSUKA LTDVerified email at dolglobal.com
yechezkel barenholzhebrew university of jerusalemVerified email at ekmd.huji.ac.il
Seng H. ChengAlexion, AstraZeneca Rare DiseaseVerified email at alexion.com
Leaf HuangProfessor Emeritus, University of North Carolina at Chapel HillVerified email at email.unc.edu
David D. Y. ChenProfessor of Chemistry, University of British ColumbiaVerified email at chem.ubc.ca
Martin GleaveProfessor of Urologic Sciences, University of British ColumbiaVerified email at ubc.ca

Pieter R Cullis

Professor Biochemistry, University of BC

Verified email at mail.ubc.ca

Drug delivery lipid nanoparticles lipid biophysics


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Drug delivery systems: entering the mainstream TM Allen, PR Cullis Science 303 (5665), 1818-1822, 2004	5720	2004
Liposomal drug delivery systems: from concept to clinical applications TM Allen, PR Cullis Advanced drug delivery reviews 65 (1), 36-48, 2013	4933	2013
Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential MJ Hope, MB Bally, G Webb, PR Cullis Biochimica et Biophysica Acta (BBA)-Biomembranes 812 (1), 55-65, 1985	2690	1985
Vesicles of variable sizes produced by a rapid extrusion procedure LD Mayer, MJ Hope, PR Cullis Biochimica et Biophysica Acta (BBA)-Biomembranes 858 (1), 161-168, 1986	2218	1986
Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ... Nature biotechnology 28 (2), 172-176, 2010	1908	2010
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo M Jayaraman, SM Ansell, BL Mui, YK Tam, J Chen, X Du, D Butler, ... Angewandte Chemie 124 (34), 8657-8661, 2012	1177	2012
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ... Nature nanotechnology 14 (12), 1084-1087, 2019	1081	2019
Lipid nanoparticle systems for enabling gene therapies PR Cullis, MJ Hope Molecular Therapy 25 (7), 1467-1475, 2017	849	2017
Liposomal compositions for enhanced retention of bioactive agents MB Bally, NL Boman, PR Cullis, LD Mayer US Patent 5,595,756, 1997	807	1997
The current landscape of nucleic acid therapeutics JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ... Nature nanotechnology 16 (6), 630-643, 2021	793	2021
Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA NM Belliveau, J Huft, PJC Lin, S Chen, AKK Leung, TJ Leaver, AW Wild, ... Molecular Therapy-Nucleic Acids 1, 2012	745	2012
On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids IM Hafez, N Maurer, PR Cullis Gene therapy 8 (15), 1188-1196, 2001	698	2001
Nomenclature for synthetic gene delivery systems PL Felgner, Y Barenholz, JP Behr, SH Cheng, P Cullis, L Huang, ... Human gene therapy 8 (5), 511-512, 1997	651	1997
Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes. A Chonn, SC Semple, PR Cullis Journal of Biological Chemistry 267 (26), 18759-18765, 1992	601	1992
Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles LD Mayer, MJ Hope, PR Cullis, AS Janoff Biochimica et Biophysica Acta (BBA)-Biomembranes 817 (1), 193-196, 1985	597	1985
Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures SC Semple, SK Klimuk, TO Harasym, N Dos Santos, SM Ansell, KF Wong, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1510 (1-2), 152-166, 2001	574	2001
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer JJ Wheeler, MB Bally, YP Zhang, DL Reimer, M Hope, PR Cullis, ... US Patent 5,976,567, 1999	553*	1999
Generation of multilamellar and unilamellar phospholipid vesicles MJ Hope, MB Bally, LD Mayer, AS Janoff, PR Cullis Chemistry and physics of lipids 40 (2-4), 89-107, 1986	543	1986
The liposomal formulation of doxorubicin SA Abraham, DN Waterhouse, LD Mayer, PR Cullis, TD Madden, ... Methods in enzymology 391, 71-97, 2005	540	2005
Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics MA Maier, M Jayaraman, S Matsuda, J Liu, S Barros, W Querbes, YK Tam, ... Molecular Therapy 21 (8), 1570-1578, 2013	513	2013

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