Pieter R Cullis
Pieter R Cullis
Professor Biochemistry, University of BC
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Cited by
Cited by
Drug delivery systems: entering the mainstream
TM Allen, PR Cullis
Science 303 (5665), 1818-1822, 2004
Liposomal drug delivery systems: from concept to clinical applications
TM Allen, PR Cullis
Advanced drug delivery reviews 65 (1), 36-48, 2013
Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential
MJ Hope, MB Bally, G Webb, PR Cullis
Biochimica et Biophysica Acta (BBA)-Biomembranes 812 (1), 55-65, 1985
Vesicles of variable sizes produced by a rapid extrusion procedure
LD Mayer, MJ Hope, PR Cullis
Biochimica et Biophysica Acta (BBA)-Biomembranes 858 (1), 161-168, 1986
Rational design of cationic lipids for siRNA delivery
SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ...
Nature biotechnology 28 (2), 172-176, 2010
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo
M Jayaraman, SM Ansell, BL Mui, YK Tam, J Chen, X Du, D Butler, ...
Angewandte Chemie 124 (34), 8657-8661, 2012
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ...
Nature nanotechnology 14 (12), 1084-1087, 2019
Liposomal compositions for enhanced retention of bioactive agents
MB Bally, NL Boman, PR Cullis, LD Mayer
US Patent 5,595,756, 1997
Lipid nanoparticle systems for enabling gene therapies
PR Cullis, MJ Hope
Molecular Therapy 25 (7), 1467-1475, 2017
Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA
NM Belliveau, J Huft, PJC Lin, S Chen, AKK Leung, TJ Leaver, AW Wild, ...
Molecular Therapy-Nucleic Acids 1, 2012
On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids
IM Hafez, N Maurer, PR Cullis
Gene therapy 8 (15), 1188-1196, 2001
Nomenclature for synthetic gene delivery systems
PL Felgner, Y Barenholz, JP Behr, SH Cheng, P Cullis, L Huang, ...
Human gene therapy 8 (5), 511-512, 1997
The current landscape of nucleic acid therapeutics
JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ...
Nature nanotechnology 16 (6), 630-643, 2021
Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles
LD Mayer, MJ Hope, PR Cullis, AS Janoff
Biochimica et Biophysica Acta (BBA)-Biomembranes 817 (1), 193-196, 1985
Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.
A Chonn, SC Semple, PR Cullis
Journal of Biological Chemistry 267 (26), 18759-18765, 1992
Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures
SC Semple, SK Klimuk, TO Harasym, N Dos Santos, SM Ansell, KF Wong, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1510 (1-2), 152-166, 2001
Generation of multilamellar and unilamellar phospholipid vesicles
MJ Hope, MB Bally, LD Mayer, AS Janoff, PR Cullis
Chemistry and physics of lipids 40 (2-4), 89-107, 1986
The liposomal formulation of doxorubicin
SA Abraham, DN Waterhouse, LD Mayer, PR Cullis, TD Madden, ...
Methods in enzymology 391, 71-97, 2005
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
JJ Wheeler, MB Bally, YP Zhang, DL Reimer, M Hope, PR Cullis, ...
US Patent 5,976,567, 1999
The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study
PR Cullis, B De Kruijff
Biochimica et Biophysica Acta (BBA)-Biomembranes 513 (1), 31-42, 1978
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