Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. JH Rothman, CT Yamashiro, CK Raymond, PM Kane, TH Stevens The Journal of cell biology 109 (1), 93-100, 1989 | 596 | 1989 |
Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance WB Derry, AP Putzke, JH Rothman Science 294 (5542), 591-595, 2001 | 586 | 2001 |
Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway JH Rothman, TH Stevens Cell 47 (6), 1041-1051, 1986 | 509 | 1986 |
PEP4 Gene of Saccharomyces cerevisiae Encodes Proteinase A, a Vacuolar Enzyme Required for Processing of Vacuolar Precursors G Ammerer, CP Hunter, JH Rothman, GC Saari, LA Valls, TH Stevens Molecular and cellular biology 6 (7), 2490-2499, 1986 | 482 | 1986 |
Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide LA Valls, CP Hunter, JH Rothman, TH Stevens Cell 48 (5), 887-897, 1987 | 415 | 1987 |
Cytokinesis and Midzone Microtubule Organization inCaenorhabditis elegans Require the Kinesin-like Protein ZEN-4 WB Raich, AN Moran, JH Rothman, J Hardin Molecular biology of the cell 9 (8), 2037-2049, 1998 | 325 | 1998 |
A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting JH Rothman, CK Raymond, T Gilbert, PJ O'Hara, TH Stevens Cell 61 (6), 1063-1074, 1990 | 322 | 1990 |
Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae. JH Rothman, I Howald, TH Stevens The EMBO journal 8 (7), 2057-2065, 1989 | 306 | 1989 |
end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos J Zhu, RJ Hill, PJ Heid, M Fukuyama, A Sugimoto, JR Priess, JH Rothman Genes & development 11 (21), 2883-2896, 1997 | 275 | 1997 |
Baculovirus p35 prevents developmentally programmed cell death and rescues a ced‐9 mutant in the nematode Caenorhabditis elegans. A Sugimoto, PD Friesen, JH Rothman The EMBO Journal 13 (9), 2023-2028, 1994 | 264 | 1994 |
Restriction of mesendoderm to a single blastomere by the combined action of SKN-1 and a GSK-3β homolog is mediated by MED-1 and-2 in C. elegans MF Maduro, MD Meneghini, B Bowerman, G Broitman-Maduro, ... Molecular cell 7 (3), 475-485, 2001 | 244 | 2001 |
Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. TH Stevens, JH Rothman, GS Payne, R Schekman The Journal of cell biology 102 (5), 1551-1557, 1986 | 241 | 1986 |
Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm MF Maduro, JH Rothman Developmental biology 246 (1), 68-85, 2002 | 228 | 2002 |
ELT-5 and ELT-6 are required continuously to regulate epidermal seam cell differentiation and cell fusion in C. elegans K Koh, JH Rothman Oxford University Press for The Company of Biologists Limited 128 (15), 2867 …, 2001 | 202 | 2001 |
Reprogramming of early embryonic blastomeres into endodermal progenitors by a Caenorhabditis elegans GATA factor J Zhu, T Fukushige, JD McGhee, JH Rothman Genes & development 12 (24), 3809-3814, 1998 | 193 | 1998 |
Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole. CJ Roberts, G Pohlig, JH Rothman, TH Stevens The Journal of cell biology 108 (4), 1363-1373, 1989 | 179 | 1989 |
Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene. JH Rothman, CP Hunter, LA Valls, TH Stevens Proceedings of the National Academy of Sciences 83 (10), 3248-3252, 1986 | 178 | 1986 |
C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline M Fukuyama, AE Rougvie, JH Rothman Current Biology 16 (8), 773-779, 2006 | 170 | 2006 |
dad‐1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates. A Sugimoto, RR Hozak, T Nakashima, T Nishimoto, JH Rothman The EMBO Journal 14 (18), 4434-4441, 1995 | 167 | 1995 |
Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans TA Bloss, ES Witze, JH Rothman Nature 424 (6952), 1066-1071, 2003 | 154 | 2003 |