Pathway and network analysis of cancer genomes Nature methods 12 (7), 615-621, 2015 | 356 | 2015 |
Computational approaches to identify functional genetic variants in cancer genomes Nature methods 10 (8), 723-729, 2013 | 187 | 2013 |
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ... Cell 163 (1), 202-217, 2015 | 179 | 2015 |
Navigating cancer network attractors for tumor-specific therapy P Creixell, EM Schoof, JT Erler, R Linding Nature biotechnology 30 (9), 842-848, 2012 | 150 | 2012 |
Exploiting temporal collateral sensitivity in tumor clonal evolution B Zhao, JC Sedlak, R Srinivas, P Creixell, JR Pritchard, B Tidor, ... Cell 165 (1), 234-246, 2016 | 133 | 2016 |
Unmasking determinants of specificity in the human kinome P Creixell, A Palmeri, CJ Miller, HJ Lou, CC Santini, M Nielsen, BE Turk, ... Cell 163 (1), 187-201, 2015 | 87 | 2015 |
Mutational properties of amino acid residues: implications for evolvability of phosphorylatable residues P Creixell, EM Schoof, CSH Tan, R Linding Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012 | 52 | 2012 |
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy J So, A Pasculescu, AY Dai, K Williton, A James, V Nguyen, P Creixell, ... Science signaling 8 (371), rs3-rs3, 2015 | 44 | 2015 |
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs B Van de Kooij, P Creixell, A van Vlimmeren, BA Joughin, CJ Miller, ... Elife 8, e44635, 2019 | 38 | 2019 |
Cells, shared memory and breaking the PTM code P Creixell, R Linding Molecular systems biology 8 (1), 598, 2012 | 34 | 2012 |
Personalized network‐based treatments in oncology X Robin, P Creixell, O Radetskaya, CC Santini, J Longden, R Linding Clinical Pharmacology & Therapeutics 94 (6), 646-650, 2013 | 24 | 2013 |
Engineering allosteric regulation in protein kinases D Pincus, JP Pandey, ZA Feder, P Creixell, O Resnekov, KA Reynolds Science signaling 11 (555), eaar3250, 2018 | 21 | 2018 |
Response to comment on “Positive selection of tyrosine loss in metazoan evolution” CSH Tan, EM Schoof, P Creixell, A Pasculescu, WA Lim, T Pawson, ... science 332 (6032), 917-917, 2011 | 18 | 2011 |
Hierarchical organization endows the kinase domain with regulatory plasticity P Creixell, JP Pandey, A Palmeri, M Bhattacharyya, M Creixell, ... Cell systems 7 (4), 371-383. e4, 2018 | 17 | 2018 |
CoreFlow: a computational platform for integration, analysis and modeling of complex biological data A Pasculescu, EM Schoof, P Creixell, Y Zheng, M Olhovsky, R Tian, J So, ... Journal of proteomics 100, 167-173, 2014 | 12 | 2014 |
Global view of the RAF-MEK-ERK module and its immediate downstream effectors CC Santini, J Longden, EM Schoof, CD Simpson, GR Jeschke, P Creixell, ... Scientific Reports 9 (1), 10865, 2019 | 11 | 2019 |
The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks B van de Kooij, FJ van der Wal, MB Rother, P Creixell, M Stout, ... bioRxiv, 2023.09. 05.556391, 2023 | | 2023 |