Pau Creixell
Pau Creixell
Koch Institute for Integrative Cancer Research at MIT
Verified email at
Cited by
Cited by
Pathway and network analysis of cancer genomes
Nature methods 12 (7), 615-621, 2015
Computational approaches to identify functional genetic variants in cancer genomes
Nature methods 10 (8), 723-729, 2013
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling
P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ...
Cell 163 (1), 202-217, 2015
Navigating cancer network attractors for tumor-specific therapy
P Creixell, EM Schoof, JT Erler, R Linding
Nature biotechnology 30 (9), 842-848, 2012
Exploiting temporal collateral sensitivity in tumor clonal evolution
B Zhao, JC Sedlak, R Srinivas, P Creixell, JR Pritchard, B Tidor, ...
Cell 165 (1), 234-246, 2016
Unmasking determinants of specificity in the human kinome
P Creixell, A Palmeri, CJ Miller, HJ Lou, CC Santini, M Nielsen, BE Turk, ...
Cell 163 (1), 187-201, 2015
Mutational properties of amino acid residues: implications for evolvability of phosphorylatable residues
P Creixell, EM Schoof, CSH Tan, R Linding
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
B Van de Kooij, P Creixell, A van Vlimmeren, BA Joughin, CJ Miller, ...
Elife 8, e44635, 2019
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
J So, A Pasculescu, AY Dai, K Williton, A James, V Nguyen, P Creixell, ...
Science signaling 8 (371), rs3-rs3, 2015
Cells, shared memory and breaking the PTM code
P Creixell, R Linding
Molecular systems biology 8 (1), 598, 2012
Engineering allosteric regulation in protein kinases
D Pincus, JP Pandey, ZA Feder, P Creixell, O Resnekov, KA Reynolds
Science signaling 11 (555), eaar3250, 2018
Personalized network‐based treatments in oncology
X Robin, P Creixell, O Radetskaya, CC Santini, J Longden, R Linding
Clinical Pharmacology & Therapeutics 94 (6), 646-650, 2013
Hierarchical organization endows the kinase domain with regulatory plasticity
P Creixell, JP Pandey, A Palmeri, M Bhattacharyya, M Creixell, ...
Cell systems 7 (4), 371-383. e4, 2018
Response to comment on “Positive selection of tyrosine loss in metazoan evolution”
CSH Tan, EM Schoof, P Creixell, A Pasculescu, WA Lim, T Pawson, ...
science 332 (6032), 917-917, 2011
Global view of the RAF-MEK-ERK module and its immediate downstream effectors
CC Santini, J Longden, EM Schoof, CD Simpson, GR Jeschke, P Creixell, ...
Scientific Reports 9 (1), 10865, 2019
CoreFlow: a computational platform for integration, analysis and modeling of complex biological data
A Pasculescu, EM Schoof, P Creixell, Y Zheng, M Olhovsky, R Tian, J So, ...
Journal of proteomics 100, 167-173, 2014
The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks
B van de Kooij, FJ van der Wal, MB Rother, P Creixell, M Stout, ...
bioRxiv, 2023
The intrinsic substrate specificity of the human tyrosine kinome
TM Yaron-Barir, BA Joughin, EM Huntsman, A Kerelsky, DM Cizin, ...
Nature, 1-8, 2024
A dual histone code specifies the binding of heterochromatin protein Rhino to a subset of piRNA source loci
A Akkouche, E Kneuss, S Bornelöv, Y Renaud, EL Eastwood, J van Lopik, ...
bioRxiv, 2024.01. 11.575256, 2024
Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
M Creixell, SD Taylor, J Gerritsen, SY Bae, M Jiang, T Augustin, M Loui, ...
bioRxiv, 2023
The system can't perform the operation now. Try again later.
Articles 1–20