Wynand Alkema
Wynand Alkema
Unknown affiliation
Verified email at
Cited by
Cited by
JASPAR: an open‐access database for eukaryotic transcription factor binding profiles
A Sandelin, W Alkema, P Engström, WW Wasserman, B Lenhard
Nucleic acids research 32 (suppl_1), D91-D94, 2004
Genome-wide analysis of mammalian promoter architecture and evolution
P Carninci, A Sandelin, B Lenhard, S Katayama, K Shimokawa, ...
Nature genetics 38 (6), 626-635, 2006
BioVenn–a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams
T Hulsen, J de Vlieg, W Alkema
BMC genomics 9, 1-6, 2008
Quantifying the accessibility of the metagenome by random expression cloning techniques
EM Gabor, WBL Alkema, DB Janssen
Environmental microbiology 6 (9), 879-886, 2004
Application of text mining in the biomedical domain
WWM Fleuren, W Alkema
Methods 74, 97-106, 2015
Literature mining for the discovery of hidden connections between drugs, genes and diseases
R Frijters, M Van Vugt, R Smeets, R Van Schaik, J De Vlieg, W Alkema
PLoS computational biology 6 (9), e1000943, 2010
High-throughput screening of a large collection of non-conventional yeasts reveals their potential for aroma formation in food fermentation
A Gamero, R Quintilla, M Groenewald, W Alkema, T Boekhout, ...
Food Microbiology 60, 147-159, 2016
Identification of functional clusters of transcription factor binding motifs in genome sequences: the MSCAN algorithm
Ö Johansson, W Alkema, WW Wasserman, J Lagergren
Bioinformatics 19 (suppl_1), i169-i176, 2003
Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor
R Frijters, W Fleuren, EJM Toonen, JP Tuckermann, HM Reichardt, ...
BMC genomics 11, 1-14, 2010
The role of hydrophobic active‐site residues in substrate specificity and acyl transfer activity of penicillin acylase
WBL Alkema, AJ Dijkhuis, E De Vries, DB Janssen
European journal of biochemistry 269 (8), 2093-2100, 2002
Characterization of the β-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies
WBL Alkema, CMH Hensgens, EH Kroezinga, E de Vries, R Floris, ...
Protein Engineering 13 (12), 857-863, 2000
CoPub: a literature-based keyword enrichment tool for microarray data analysis
R Frijters, B Heupers, P van Beek, M Bouwhuis, R van Schaik, J de Vlieg, ...
Nucleic acids research 36 (suppl_2), W406-W410, 2008
MSCAN: identification of functional clusters of transcription factor binding sites
WBL Alkema, Ö Johansson, J Lagergren, WW Wasserman
Nucleic acids research 32 (suppl_2), W195-W198, 2004
Microbial bioinformatics for food safety and production
W Alkema, J Boekhorst, M Wels, SAFT van Hijum
Briefings in Bioinformatics 17 (2), 283-292, 2016
Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells
MML Linssen, DH Van Raalte, EJM Toonen, W Alkema, GC Van der Zon, ...
Cellular signalling 23 (11), 1708-1715, 2011
Regulog analysis: detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus
WBL Alkema, B Lenhard, WW Wasserman
Genome research 14 (7), 1362-1373, 2004
Hydrogenosomes in the anaerobic fungus Neocallimastix frontalis have a double membrane but lack an associated organelle genome
M van der Giezen, KA Sjollema, RRE Artz, W Alkema, RA Prins
FEBS letters 408 (2), 147-150, 1997
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling
RL Smeets, WWM Fleuren, X He, PM Vink, F Wijnands, M Gorecka, ...
BMC immunology 13, 1-17, 2012
Live biotherapeutic products, a road map for safety assessment
A Rouanet, S Bolca, A Bru, I Claes, H Cvejic, H Girgis, A Harper, ...
Frontiers in Medicine 7, 534182, 2020
Magnesium prevents vascular calcification in Klotho deficiency
AD Ter Braake, AE Smit, C Bos, AE van Herwaarden, W Alkema, ...
Kidney International 97 (3), 487-501, 2020
The system can't perform the operation now. Try again later.
Articles 1–20