A bivalent chromatin structure marks key developmental genes in embryonic stem cells BE Bernstein, TS Mikkelsen, X Xie, M Kamal, DJ Huebert, J Cuff, B Fry, ... Cell 125 (2), 315-326, 2006 | 6277 | 2006 |
Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 6251 | 2015 |
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells TS Mikkelsen, M Ku, DB Jaffe, B Issac, E Lieberman, G Giannoukos, ... Nature 448 (7153), 553-560, 2007 | 4955 | 2007 |
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state M Wernig, A Meissner, R Foreman, T Brambrink, M Ku, K Hochedlinger, ... Nature 448 (7151), 318-324, 2007 | 3568 | 2007 |
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA L Warren, PD Manos, T Ahfeldt, YH Loh, H Li, F Lau, W Ebina, PK Mandal, ... Cell stem cell 7 (5), 618-630, 2010 | 3439 | 2010 |
DNA methylation: roles in mammalian development ZD Smith, A Meissner Nature Reviews Genetics 14 (3), 204-220, 2013 | 3388 | 2013 |
Genome-scale DNA methylation maps of pluripotent and differentiated cells A Meissner, TS Mikkelsen, H Gu, M Wernig, J Hanna, A Sivachenko, ... Nature 454 (7205), 766-770, 2008 | 3017 | 2008 |
The mammalian epigenome BE Bernstein, A Meissner, ES Lander Cell 128 (4), 669-681, 2007 | 2831 | 2007 |
lincRNAs act in the circuitry controlling pluripotency and differentiation M Guttman, J Donaghey, BW Carey, M Garber, JK Grenier, G Munson, ... Nature 477 (7364), 295-300, 2011 | 2194 | 2011 |
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin J Hanna, M Wernig, S Markoulaki, CW Sun, A Meissner, JP Cassady, ... Science 318 (5858), 1920-1923, 2007 | 2148 | 2007 |
Targeted deletion reveals essential and overlapping functions of the miR-17∼ 92 family of miRNA clusters A Ventura, AG Young, MM Winslow, L Lintault, A Meissner, SJ Erkeland, ... Cell 132 (5), 875-886, 2008 | 2032 | 2008 |
The NIH roadmap epigenomics mapping consortium BE Bernstein, JA Stamatoyannopoulos, JF Costello, B Ren, ... Nature biotechnology 28 (10), 1045-1048, 2010 | 1920 | 2010 |
Dissecting direct reprogramming through integrative genomic analysis TS Mikkelsen, J Hanna, X Zhang, M Ku, M Wernig, P Schorderet, ... Nature 454 (7200), 49-55, 2008 | 1875 | 2008 |
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2 WG Chen, Q Chang, Y Lin, A Meissner, AE West, EC Griffith, R Jaenisch, ... Science 302 (5646), 885-889, 2003 | 1495 | 2003 |
Charting a dynamic DNA methylation landscape of the human genome MJ Ziller, H Gu, F Müller, J Donaghey, LTY Tsai, O Kohlbacher, ... Nature 500 (7463), 477-481, 2013 | 1457 | 2013 |
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis A Meissner, A Gnirke, GW Bell, B Ramsahoye, ES Lander, R Jaenisch Nucleic acids research 33 (18), 5868-5877, 2005 | 1404 | 2005 |
Dnmt3a is essential for hematopoietic stem cell differentiation GA Challen, D Sun, M Jeong, M Luo, J Jelinek, JS Berg, C Bock, ... Nature genetics 44 (1), 23-31, 2012 | 1295 | 2012 |
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals BR Carone, L Fauquier, N Habib, JM Shea, CE Hart, R Li, C Bock, C Li, ... Cell 143 (7), 1084-1096, 2010 | 1285 | 2010 |
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines C Bock, E Kiskinis, G Verstappen, H Gu, G Boulting, ZD Smith, M Ziller, ... Cell 144 (3), 439-452, 2011 | 1156 | 2011 |
A unique regulatory phase of DNA methylation in the early mammalian embryo ZD Smith, MM Chan, TS Mikkelsen, H Gu, A Gnirke, A Regev, A Meissner Nature 484 (7394), 339-344, 2012 | 1122 | 2012 |