| Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice M Themis, SN Waddington, M Schmidt, C Von Kalle, Y Wang, F Al-Allaf, ... Molecular Therapy 12 (4), 763-771, 2005 | 282 | 2005 |
| Hepatic stem cells: from inside and outside the liver? MR Alison, P Vig, F Russo, BW Bigger, E Amofah, M Themis, S Forbes Cell proliferation 37 (1), 1-21, 2004 | 211 | 2004 |
| Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy SN Waddington, MS Nivsarkar, AR Mistry, SMK Buckley, G Kemball-Cook, ... Blood 104 (9), 2714-2721, 2004 | 151 | 2004 |
| Widespread Distribution and Muscle Differentiation of Human Fetal Mesenchymal Stem Cells After Intrauterine Transplantation in Dystrophic mdx Mouse J Chan, SN Waddington, K O'Donoghue, H Kurata, PV Guillot, ... Stem cells 25 (4), 875-884, 2007 | 150 | 2007 |
| In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor SN Waddington, SMK Buckley, M Nivsarkar, S Jezzard, H Schneider, ... Blood, The Journal of the American Society of Hematology 101 (4), 1359-1366, 2003 | 123 | 2003 |
| Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1 ER Eden, DD Patel, XM Sun, JJ Burden, M Themis, M Edwards, P Lee, ... The Journal of clinical investigation 110 (11), 1695-1702, 2002 | 100 | 2002 |
| Construction and characterization of a highly stable human: rodent monochromosomal hybrid panel for genetic complementation and genome mapping studies AP Cuthbert, DA Trott, RM Ekong, S Jezzard, NL England, M Themis, ... Cytogenetic and Genome Research 71 (1), 68-76, 1995 | 99 | 1995 |
| Three-dimensional cell culture: from evolution to revolution S Alhaque, M Themis, H Rashidi Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 94 | 2018 |
| Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the … M Themis, H Schneider, T Kiserud, T Cook, S Adebakin, S Jezzard, ... Gene Therapy 6 (7), 1239-1248, 1999 | 93 | 1999 |
| Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus AM Douar, S Adebakin, M Themis, A Pavirani, T Cook, C Coutelle Gene Therapy 4 (9), 883-890, 1997 | 91 | 1997 |
| Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype NL Kennea, SN Waddington, J Chan, K O’Donoghue, D Yeung, DL Taylor, ... Cell Cycle 8 (7), 1069-1079, 2009 | 87 | 2009 |
| Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice SN Waddington, KA Mitrophanous, FM Ellard, SMK Buckley, M Nivsarkar, ... Gene therapy 10 (15), 1234-1240, 2003 | 87 | 2003 |
| LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives FA Al-Allaf, C Coutelle, SN Waddington, AL David, R Harbottle, M Themis International archives of medicine 3 (1), 36, 2010 | 81 | 2010 |
| Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo LG Gregory, RP Harbottle, L Lawrence, HJ Knapton, M Themis, ... Molecular therapy 7 (1), 19-26, 2003 | 75 | 2003 |
| In utero gene therapy: current challenges and perspectives SN Waddington, MG Kramer, R Hernandez-Alcoceba, SMK Buckley, ... Molecular Therapy 11 (5), 661-676, 2005 | 72 | 2005 |
| Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the β-galactosidase and human factor IX genes to early gestation fetal sheep in utero A David, T Cook, S Waddington, D Peebles, M Nivsarkar, H Knapton, ... Human gene therapy 14 (4), 353-364, 2003 | 72 | 2003 |
| Sustained delivery of therapeutic concentrations of human clotting factor IX – a comparison of adenoviral and AAV vectors administered in utero H Schneider, C Mühle, A Marie Douar, S Waddington, QJ Jiang, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2002 | 72 | 2002 |
| Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX BW Bigger, EK Siapati, A Mistry, SN Waddington, MS Nivsarkar, L Jacobs, ... Gene therapy 13 (2), 117-126, 2006 | 70 | 2006 |
| Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero D Peebles, LG Gregory, A David, M Themis, SN Waddington, HJ Knapton, ... Gene therapy 11 (1), 70-78, 2004 | 66 | 2004 |
| Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression SMK Buckley, SJ Howe, V Sheard, NJ Ward, C Coutelle, AJ Thrasher, ... Gene therapy 15 (16), 1167-1175, 2008 | 65 | 2008 |
