Stephane Angers
Stephane Angers
Director and Professor, Donnelly Centre, University of Toronto
Verified email at - Homepage
Cited by
Cited by
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
Proximal events in Wnt signal transduction
S Angers, RT Moon
Nature Reviews Molecular Cell Biology 10 (7), 468-477, 2009
Detection of β2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
S Angers, A Salahpour, E Joly, S Hilairet, D Chelsky, M Dennis, M Bouvier
Proceedings of the National Academy of Sciences 97 (7), 3684, 2000
Gli proteins in development and disease
C Hui, S Angers
Annual review of cell and developmental biology 27 (1), 513-537, 2011
Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery
S Angers, T Li, X Yi, MJ MacCoss, RT Moon, N Zheng
Nature 443 (7111), 590-593, 2006
Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function
S Angers, A Salahpour, M Bouvier
Annual review of pharmacology and toxicology 42 (1), 409-435, 2002
Wnt signaling in development and tissue homeostasis
Z Steinhart, S Angers
Development 145 (11), dev146589, 2018
High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies
JY Youn, WH Dunham, SJ Hong, JDR Knight, M Bashkurov, GI Chen, ...
Molecular cell 69 (3), 517-532. e11, 2018
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants
JP Morello, A Salahpour, A Laperrière, V Bernier, MF Arthus, M Lonergan, ...
The Journal of clinical investigation 105 (7), 887-895, 2000
β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
M Azzi, PG Charest, S Angers, G Rousseau, T Kohout, M Bouvier, ...
Proceedings of the National Academy of Sciences 100 (20), 11406-11411, 2003
Quantitative assessment of β1-and β2-adrenergic receptor homo-and heterodimerization by bioluminescence resonance energy transfer
JF Mercier, A Salahpour, S Angers, A Breit, M Bouvier
Journal of Biological Chemistry 277 (47), 44925, 2002
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
HF Farin, I Jordens, MH Mosa, O Basak, J Korving, DVF Tauriello, ...
Nature 530 (7590), 340-343, 2016
Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling
MB Major, ND Camp, JD Berndt, XH Yi, SJ Goldenberg, C Hubbert, ...
Science 316 (5827), 1043, 2007
The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation
S Angers, CJ Thorpe, TL Biechele, SJ Goldenberg, N Zheng, ...
Nature cell biology 8 (4), 348-357, 2006
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
A Fernandez-L, PA Northcott, J Dalton, C Fraga, D Ellison, S Angers, ...
Genes & development 23 (23), 2729-2741, 2009
Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer
MA Ayoub, C Couturier, E Lucas-Meunier, S Angers, P Fossier, M Bouvier, ...
Journal of Biological Chemistry 277 (24), 21522, 2002
Glutamate transporter coupling to Na, K-ATPase
EM Rose, JCP Koo, JE Antflick, SM Ahmed, S Angers, DR Hampson
The Journal of Neuroscience 29 (25), 8143-8155, 2009
Homodimerization of the β2-adrenergic receptor as a prerequisite for cell surface targeting
A Salahpour, S Angers, JF Mercier, M Lagacé, S Marullo, M Bouvier
Journal of Biological Chemistry 279 (32), 33390-33397, 2004
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ...
Nature 559 (7713), 285-289, 2018
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60-68, 2017
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