| Predicting functional effect of human missense mutations using PolyPhen‐2 I Adzhubei, DM Jordan, SR Sunyaev Current protocols in human genetics 76 (1), 7.20. 1-7.20. 41, 2013 | 3844 | 2013 |
| Evolution and functional impact of rare coding variation from deep sequencing of human exomes JA Tennessen, AW Bigham, TD O’connor, W Fu, EE Kenny, S Gravel, ... science 337 (6090), 64-69, 2012 | 1903 | 2012 |
| Widespread macromolecular interaction perturbations in human genetic disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015 | 581 | 2015 |
| Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii I Seim, X Fang, Z Xiong, AV Lobanov, Z Huang, S Ma, Y Feng, ... Nature communications 4, 2212, 2013 | 292 | 2013 |
| Estimating the selective effects of heterozygous protein-truncating variants from human exome data CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ... Nature genetics 49 (5), 806, 2017 | 156 | 2017 |
| Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ... Nature communications 10 (1), 790, 2019 | 118 | 2019 |
| No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study DM Jordan, HK Choi, M Verbanck, R Topless, HH Won, G Nadkarni, ... PLoS medicine 16 (1), e1002725, 2019 | 115 | 2019 |
| Identification of cis-suppression of human disease mutations by comparative genomics DM Jordan, SG Frangakis, C Golzio, CA Cassa, J Kurtzberg, EE Davis, ... Nature 524 (7564), 225, 2015 | 113 | 2015 |
| Large numbers of genetic variants considered to be pathogenic are common in asymptomatic individuals CA Cassa, MY Tong, DM Jordan Human mutation 34 (9), 1216-1220, 2013 | 105 | 2013 |
| Disproportionate contributions of select genomic compartments and cell types to genetic risk for coronary artery disease HH Won, P Natarajan, A Dobbyn, DM Jordan, P Roussos, K Lage, ... PLoS genetics 11 (10), e1005622, 2015 | 104 | 2015 |
| Development and validation of a computational method for assessment of missense variants in hypertrophic cardiomyopathy DM Jordan, A Kiezun, SM Baxter, V Agarwala, RC Green, MF Murray, ... The American Journal of Human Genetics 88 (2), 183-192, 2011 | 94 | 2011 |
| Human allelic variation: perspective from protein function, structure, and evolution DM Jordan, VE Ramensky, SR Sunyaev Current opinion in structural biology 20 (3), 342-350, 2010 | 89 | 2010 |
| Excess of deleterious mutations around HLA genes reveals evolutionary cost of balancing selection TL Lenz, V Spirin, DM Jordan, SR Sunyaev Molecular biology and evolution 33 (10), 2555-2564, 2016 | 69 | 2016 |
| Mitigating false‐positive associations in rare disease gene discovery S Akle, S Chun, DM Jordan, CA Cassa Human mutation 36 (10), 998-1003, 2015 | 21 | 2015 |
| Using full genomic information to predict disease: breaking down the barriers between complex and Mendelian diseases DM Jordan, R Do Annual review of genomics and human genetics 19, 289-301, 2018 | 19 | 2018 |
| The landscape of pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases DM Jordan, M Verbanck, R Do Available at SSRN 3188410, 2018 | 14 | 2018 |
| Parameterization of peptide 13C carbonyl chemical shielding anisotropy in molecular dynamics simulations DM Jordan, KM Mills, I Andricioaei, A Bhattacharya, K Palmo, ... ChemPhysChem 8 (9), 1375-1385, 2007 | 5 | 2007 |
| Reply to ‘Selective effects of heterozygous protein-truncating variants’ CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ... Nature genetics 51 (1), 3, 2019 | 3 | 2019 |
| When “N of 2” is not enough: integrating statistical and functional data in gene discovery CA Cassa, S Akle, DM Jordan, JA Rosenfeld Molecular Case Studies 3 (3), a001099, 2017 | 3 | 2017 |
| A literature review at genome scale: improving clinical variant assessment CA Cassa, DM Jordan, I Adzhubei, S Sunyaev Genetics in Medicine 20 (9), 936, 2018 | 1 | 2018 |
