Stem cell gene expression programs influence clinical outcome in human leukemia K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ... Nature medicine 17 (9), 1086-1093, 2011 | 1211 | 2011 |
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis SH Kim, ER Lechman, N Bianco, R Menon, A Keravala, J Nash, Z Mi, ... The Journal of Immunology 174 (10), 6440-6448, 2005 | 454 | 2005 |
Comparison of human cord blood engraftment between immunocompromised mouse strains SP McDermott, K Eppert, ER Lechman, M Doedens, JE Dick Blood, The Journal of the American Society of Hematology 116 (2), 193-200, 2010 | 375 | 2010 |
Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor α soluble receptors to rabbit knees with experimental arthritis has local and distal anti … SC Ghivizzani, ER Lechman, R Kang, C Tio, J Kolls, CH Evans, ... Proceedings of the National Academy of Sciences 95 (8), 4613-4618, 1998 | 349 | 1998 |
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal M Milyavsky, OI Gan, M Trottier, M Komosa, O Tabach, F Notta, ... Cell stem cell 7 (2), 186-197, 2010 | 337 | 2010 |
miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ... Cancer cell 29 (2), 214-228, 2016 | 296 | 2016 |
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies EM Schoof, B Furtwängler, N Üresin, N Rapin, S Savickas, C Gentil, ... Nature communications 12 (1), 3341, 2021 | 291 | 2021 |
Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive SH Kim, N Bianco, R Menon, ER Lechman, WJ Shufesky, AE Morelli, ... Molecular therapy 13 (2), 289-300, 2006 | 267 | 2006 |
Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws JD Whalen, EL Lechman, CA Carlos, K Weiss, I Kovesdi, JC Glorioso, ... The journal of immunology 162 (6), 3625-3632, 1999 | 262 | 1999 |
Attenuation of miR-126 activity expands HSC in vivo without exhaustion ER Lechman, B Gentner, P van Galen, A Giustacchini, M Saini, ... Cell stem cell 11 (6), 799-811, 2012 | 239 | 2012 |
Identification of hematopoietic stem cell–specific miRNAs enables gene therapy of globoid cell leukodystrophy B Gentner, I Visigalli, H Hiramatsu, E Lechman, S Ungari, A Giustacchini, ... Science translational medicine 2 (58), 58ra84-58ra84, 2010 | 236 | 2010 |
Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees ER Lechman, D Jaffurs, SC Ghivizzani, A Gambotto, I Kovesdi, Z Mi, ... The Journal of Immunology 163 (4), 2202-2208, 1999 | 185 | 1999 |
Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. SC Ghivizzani, R Kang, HI Georgescu, ER Lechman, D Jaffurs, JM Engle, ... Journal of immunology (Baltimore, Md.: 1950) 159 (7), 3604-3612, 1997 | 179 | 1997 |
Adenovirus‐mediated gene transfer of insulin‐like growth factor 1 stimulates proteoglycan synthesis in rabbit joints Z Mi, SC Ghivizzani, ER Lechman, D Jaffurs, JC Glorioso, CH Evans, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 148 | 2000 |
Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis T Oligino, SC Ghivizzani, D Wolfe, ER Lechman, D Krisky, Z Mi, CH Evans, ... Gene therapy 6 (10), 1713-1720, 1999 | 146 | 1999 |
Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees Z Mi, SC Ghivizzani, E Lechman, JC Glorioso, CH Evans, PD Robbins Arthritis Res Ther 5, 1-8, 2003 | 145 | 2003 |
Ex vivo gene delivery of IL-1Ra and soluble TNF receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis SH Kim, ER Lechman, S Kim, J Nash, TJ Oligino, PD Robbins Molecular Therapy 6 (5), 591-600, 2002 | 114 | 2002 |
Direct retrovirus-mediated gene transfer to the synovium of the rabbit knee: implications for arthritis gene therapy SC Ghivizzani, ER Lechman, C Tio, KM Mule, S Chada, JE McCormack, ... Gene Therapy 4 (9), 977-982, 1997 | 113 | 1997 |
Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium Z Mi, X Lu, JC Mai, BG Ng, G Wang, ER Lechman, SC Watkins, ... Molecular Therapy 8 (2), 295-305, 2003 | 99 | 2003 |
Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion P van Galen, A Kreso, E Wienholds, E Laurenti, K Eppert, ER Lechman, ... Cell stem cell 14 (1), 94-106, 2014 | 97 | 2014 |