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Nathan Basisty
Nathan Basisty
Investigator, National Institute on Aging, NIH
Verified email at nih.gov - Homepage
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Year
A proteomic atlas of senescence-associated secretomes for aging biomarker development
N Basisty, A Kale, OH Jeon, C Kuehnemann, T Payne, C Rao, A Holtz, ...
PLoS biology 18 (1), e3000599, 2020
7532020
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart
DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ...
Aging cell 13 (3), 529-539, 2014
3172014
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ...
Nature metabolism 2 (11), 1265-1283, 2020
2252020
Global proteomics and pathway analysis of pressure-overload–induced heart failure and its attenuation by mitochondrial-targeted peptides
DF Dai, EJ Hsieh, T Chen, LG Menendez, NB Basisty, L Tsai, RP Beyer, ...
Circulation: Heart Failure 6 (5), 1067-1076, 2013
1542013
Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions
DG Christensen, X Xie, N Basisty, J Byrnes, S McSweeney, B Schilling, ...
Frontiers in Microbiology 10, 1604, 2019
1462019
Mitochondrial dysfunction in cardiac aging
A Tocchi, EK Quarles, N Basisty, L Gitari, PS Rabinovitch
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (11), 1424-1433, 2015
1372015
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts
YA Chiao, SC Kolwicz, N Basisty, A Gagnidze, J Zhang, H Gu, D Djukovic, ...
Aging (Albany NY) 8 (2), 314, 2016
1142016
SILAC analysis reveals increased secretion of hemostasis-related factors by senescent cells
CD Wiley, S Liu, C Limbad, AM Zawadzka, J Beck, M Demaria, R Artwood, ...
Cell reports 28 (13), 3329-3337. e5, 2019
1122019
Protein turnover in aging and longevity
N Basisty, JG Meyer, B Schilling
Proteomics 18 (5-6), 1700108, 2018
1042018
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects
PP Karunadharma, N Basisty, DF Dai, YA Chiao, EK Quarles, EJ Hsieh, ...
Aging cell 14 (4), 547-557, 2015
1012015
Mechanisms, detection, and relevance of protein acetylation in prokaryotes
DG Christensen, JT Baumgartner, X Xie, KM Jew, N Basisty, B Schilling, ...
MBio 10 (2), 10.1128/mbio. 02708-18, 2019
982019
Algorithmic assessment of cellular senescence in experimental and clinical specimens
J Kohli, B Wang, SM Brandenburg, N Basisty, K Evangelou, ...
Nature protocols 16 (5), 2471-2498, 2021
912021
Sirtuin 5 regulates proximal tubule fatty acid oxidation to protect against AKI
T Chiba, KD Peasley, KR Cargill, KV Maringer, SS Bharathi, E Mukherjee, ...
Journal of the American Society of Nephrology: JASN 30 (12), 2384, 2019
892019
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast
CJ Murakami, V Wall, N Basisty, M Kaeberlein
PloS one 6 (9), e24530, 2011
882011
Plasma proteomic biomarker signature of age predicts health and life span
T Tanaka, N Basisty, G Fantoni, J Candia, AZ Moore, A Biancotto, ...
Elife 9, e61073, 2020
872020
Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant
A Boominathan, S Vanhoozer, N Basisty, K Powers, AL Crampton, ...
Nucleic acids research 44 (19), 9342-9357, 2016
782016
Mitochondrial-targeted catalase: extended longevity and the roles in various disease models
DF Dai, YA Chiao, GM Martin, DJ Marcinek, N Basisty, EK Quarles, ...
Progress in Molecular Biology and Translational Science 146, 203-241, 2017
762017
Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice
YA Chiao, H Zhang, M Sweetwyne, J Whitson, YS Ting, N Basisty, ...
Elife 9, e55513, 2020
742020
Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment
E Quarles, N Basisty, YA Chiao, G Merrihew, H Gu, MT Sweetwyne, ...
Aging Cell 19 (2), e13086, 2020
742020
Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner
SE Kruse, PP Karunadharma, N Basisty, R Johnson, RP Beyer, ...
Aging Cell 15 (1), 89-99, 2016
732016
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