Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells Y Taniguchi*, PJ Choi*, GW Li*, H Chen*, et al, *equal contribution Science 329 (5991), 533, 2010 | 2314 | 2010 |
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system B Chen, LA Gilbert, BA Cimini, J Schnitzbauer, W Zhang, GW Li, J Park, ... Cell 155 (7), 1479-1491, 2013 | 2265 | 2013 |
Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources GW Li, D Burkhardt, C Gross, JS Weissman Cell 157 (3), 624-635, 2014 | 1395 | 2014 |
Probing transcription factor dynamics at the single-molecule level in a living cell J Elf*, GW Li*, XS Xie, *equal contribution Science 316 (5828), 1191, 2007 | 1251 | 2007 |
The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria GW Li, E Oh, JS Weissman Nature, 2012 | 785 | 2012 |
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ... Cell 151 (5), 1042-1054, 2012 | 665 | 2012 |
Central dogma at the single-molecule level in living cells GW Li, XS Xie Nature 475 (7356), 308-315, 2011 | 518 | 2011 |
Chromosome Organization by a Nucleoid-Associated Protein in Live Bacteria W Wang*, GW Li*, C Chen*, XS Xie, X Zhuang, *equal contribution Science 333 (6048), 1445-1449, 2011 | 441 | 2011 |
Single-molecule approach to molecular biology in living bacterial cells XS Xie, PJ Choi, GW Li, NK Lee, G Lia Annu. Rev. Biophys. 37 (1), 417-444, 2008 | 426 | 2008 |
Effects of macromolecular crowding and DNA looping on gene regulation kinetics GW Li, OG Berg, J Elf Nature Physics 5 (4), 294-297, 2009 | 260 | 2009 |
Evolutionary convergence of pathway-specific enzyme expression stoichiometry JB Lalanne, JC Taggart, MS Guo, L Herzel, A Schieler, GW Li Cell 173 (3), 749-761. e38, 2018 | 181 | 2018 |
A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation Y Zhang, DH Burkhardt, S Rouskin, GW Li*, JS Weissman*, CA Gross*, ... Molecular cell 70 (2), 274-286. e7, 2018 | 180 | 2018 |
Operon mRNAs are organized into ORF-centric structures that predict translation efficiency DH Burkhardt, S Rouskin, Y Zhang, GW Li*, JS Weissman*, CA Gross*, ... Elife 6, e22037, 2017 | 163 | 2017 |
The Coding and Noncoding Architecture of the Caulobacter crescentus Genome JM Schrader, B Zhou, GW Li, K Lasker, WS Childers, B Williams, T Long, ... PLoS genetics 10 (7), e1004463, 2014 | 149 | 2014 |
Functionally uncoupled transcription–translation in Bacillus subtilis GE Johnson, JB Lalanne, ML Peters, GW Li Nature 585 (7823), 124-128, 2020 | 142 | 2020 |
Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus AS DeFrancesco, N Masloboeva, AK Syed, A DeLoughery, N Bradshaw, ... Proceedings of the National Academy of Sciences 114 (29), E5969-E5978, 2017 | 113 | 2017 |
From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions M Mori, Z Zhang, A Banaei‐Esfahani, JB Lalanne, H Okano, BC Collins, ... Molecular systems biology 17 (5), e9536, 2021 | 93 | 2021 |
How do bacteria tune translation efficiency? GW Li Current opinion in microbiology 24, 66-71, 2015 | 91 | 2015 |
Keeping the proportions of protein complex components in check JC Taggart, H Zauber, M Selbach, GW Li, E McShane Cell systems 10 (2), 125-132, 2020 | 89 | 2020 |
Production of protein-complex components is stoichiometric and lacks general feedback regulation in eukaryotes JC Taggart, GW Li Cell systems 7 (6), 580-589. e4, 2018 | 88 | 2018 |