| Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche T Sato, RG Vries, HJ Snippert, M Van De Wetering, N Barker, DE Stange, ... Nature 459 (7244), 262-265, 2009 | 6159 | 2009 |
| Identification of stem cells in small intestine and colon by marker gene Lgr5 N Barker, JH Van Es, J Kuipers, P Kujala, M Van Den Born, M Cozijnsen, ... Nature 449 (7165), 1003-1007, 2007 | 5900 | 2007 |
| Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 V Korinek, N Barker, P Moerer, E van Donselaar, G Huls, PJ Peters, ... Nature genetics 19 (4), 379-383, 1998 | 1976 | 1998 |
| Lgr5+ ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro N Barker, M Huch, P Kujala, M van de Wetering, HJ Snippert, JH van Es, ... Cell stem cell 6 (1), 25-36, 2010 | 1641 | 2010 |
| SARS-CoV-2 productively infects human gut enterocytes MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... Science 369 (6499), 50-54, 2020 | 1583 | 2020 |
| Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011 | 1317 | 2011 |
| M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells N van der Wel, D Hava, D Houben, D Fluitsma, M van Zon, J Pierson, ... Cell 129 (7), 1287-1298, 2007 | 1121 | 2007 |
| Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. PJ Peters, J Borst, V Oorschot, M Fukuda, O Krähenbühl, J Tschopp, ... The Journal of experimental medicine 173 (5), 1099-1109, 1991 | 868 | 1991 |
| Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments PJ Peters, JJ Neefjes, V Oorschot, HL Ploegh, HJ Geuze Nature 349 (6311), 669-676, 1991 | 826 | 1991 |
| Transcription factor achaete scute-like 2 controls intestinal stem cell fate LG van der Flier, ME van Gijn, P Hatzis, P Kujala, A Haegebarth, ... Cell 136 (5), 903-912, 2009 | 765 | 2009 |
| Cell-type and tissue-specific expression of caveolin-2: caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo PE Scherer, RY Lewis, D Volonté, JA Engelman, F Galbiati, J Couet, ... Journal of Biological Chemistry 272 (46), 29337-29346, 1997 | 685 | 1997 |
| In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection S Bartfeld, T Bayram, M van de Wetering, M Huch, H Begthel, P Kujala, ... Gastroenterology 148 (1), 126-136. e6, 2015 | 680 | 2015 |
| Long‐term expanding human airway organoids for disease modeling N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ... The EMBO journal 38 (4), e100300, 2019 | 657 | 2019 |
| Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD AF Baas, J Kuipers, NN van der Wel, E Batlle, HK Koerten, PJ Peters, ... Cell 116 (3), 457-466, 2004 | 575 | 2004 |
| The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route JJ Neefjes, V Stollorz, PJ Peters, HJ Geuze, HL Ploegh Cell 61 (1), 171-183, 1990 | 562 | 1990 |
| CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. MJ Metzelaar, PL Wijngaard, PJ Peters, JJ Sixma, HK Nieuwenhuis, ... Journal of Biological Chemistry 266 (5), 3239-3245, 1991 | 533 | 1991 |
| Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria L Griparic, NN Van Der Wel, IJ Orozco, PJ Peters, AM Van Der Bliek Journal of Biological Chemistry 279 (18), 18792-18798, 2004 | 531 | 2004 |
| Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606. e19, 2018 | 515 | 2018 |
| Visualization of a short-range Wnt gradient in the intestinal stem-cell niche HF Farin, I Jordens, MH Mosa, O Basak, J Korving, DVF Tauriello, ... Nature 530 (7590), 340-343, 2016 | 514 | 2016 |
| Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ... Cell 155 (2), 357-368, 2013 | 489 | 2013 |
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
