| Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes NR Jana, P Dikshit, A Goswami, S Kotliarova, S Murata, K Tanaka, ... Journal of Biological Chemistry 280 (12), 11635-11640, 2005 | 375 | 2005 |
| Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein PO Bauer, A Goswami, HK Wong, M Okuno, M Kurosawa, M Yamada, ... Nature biotechnology 28 (3), 256-263, 2010 | 274 | 2010 |
| Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway NR Jana, P Dikshit, A Goswami, N Nukina Journal of Biological Chemistry 279 (12), 11680-11685, 2004 | 274 | 2004 |
| NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients S Johann, M Heitzer, M Kanagaratnam, A Goswami, T Rizo, J Weis, ... Glia 63 (12), 2260-2273, 2015 | 262 | 2015 |
| Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, ... Nature communications 9 (1), 335, 2018 | 261 | 2018 |
| Aspirin induces apoptosis through the inhibition of proteasome function P Dikshit, M Chatterjee, A Goswami, A Mishra, NR Jana Journal of Biological Chemistry 281 (39), 29228-29235, 2006 | 177 | 2006 |
| Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis J Prause, A Goswami, I Katona, A Roos, M Schnizler, E Bushuven, ... Human molecular genetics 22 (8), 1581-1600, 2013 | 167 | 2013 |
| Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism HK Wong, PO Bauer, M Kurosawa, A Goswami, C Washizu, Y Machida, ... Human molecular genetics 17 (20), 3223-3235, 2008 | 152 | 2008 |
| Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction A Goswami, P Dikshit, A Mishra, S Mulherkar, N Nukina, NR Jana Biochemical and biophysical research communications 342 (1), 184-190, 2006 | 150 | 2006 |
| Inhibition of Rho kinases enhances the degradation of mutant huntingtin PO Bauer, HK Wong, F Oyama, A Goswami, M Okuno, Y Kino, H Miyazaki, ... Journal of Biological Chemistry 284 (19), 13153-13164, 2009 | 128 | 2009 |
| Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS A Filézac de L'Etang, N Maharjan, M Cordeiro Braña, C Ruegsegger, ... Nature neuroscience 18 (2), 227-238, 2015 | 109 | 2015 |
| FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy L Marrone, HCA Drexler, J Wang, P Tripathi, T Distler, P Heisterkamp, ... Acta neuropathologica 138, 67-84, 2019 | 108 | 2019 |
| The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins A Mishra, SK Godavarthi, M Maheshwari, A Goswami, NR Jana Journal of biological chemistry 284 (16), 10537-10545, 2009 | 108 | 2009 |
| Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances JT Vollrath, A Sechi, A Dreser, I Katona, D Wiemuth, J Vervoorts, ... Cell death & disease 5 (6), e1290-e1290, 2014 | 102 | 2014 |
| The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins A Dreser, JT Vollrath, A Sechi, S Johann, A Roos, A Yamoah, I Katona, ... Cell Death & Differentiation 24 (10), 1655-1671, 2017 | 99 | 2017 |
| Curcumin induces stress response, neurite outgrowth and prevent NF-κB activation by inhibiting the proteasome function P Dikshit, A Goswami, A Mishra, M Catterjee, N Ranjan Jana Neurotoxicity Research 9, 29-37, 2006 | 91 | 2006 |
| Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis M Naumann, K Peikert, R Günther, AJ van der Kooi, E Aronica, A Hübers, ... Annals of clinical and translational neurology 6 (12), 2384-2394, 2019 | 63 | 2019 |
| Myopathy in Marinesco–Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology A Roos, S Buchkremer, L Kollipara, T Labisch, C Gatz, M Zitzelsberger, ... Acta neuropathologica 127, 761-777, 2014 | 60 | 2014 |
| Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS C Ruegsegger, N Maharjan, A Goswami, A Filézac de L’Etang, J Weis, ... Acta neuropathologica 131, 427-451, 2016 | 56 | 2016 |
| Cuprizone‐induced graded oligodendrocyte vulnerability is regulated by the transcription factor DNA damage‐inducible transcript 3 F Fischbach, J Nedelcu, P Leopold, J Zhan, T Clarner, L Nellessen, ... Glia 67 (2), 263-276, 2019 | 52 | 2019 |
