The inflammasomes K Schroder, J Tschopp cell 140 (6), 821-832, 2010 | 6579 | 2010 |
Interferon-γ: an overview of signals, mechanisms and functions K Schroder, PJ Hertzog, T Ravasi, DA Hume Journal of Leucocyte Biology 75 (2), 163-189, 2004 | 5757 | 2004 |
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muñoz-Planillo, ... Nature medicine 21 (3), 248-255, 2015 | 2479 | 2015 |
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? J Tschopp, K Schroder Nature reviews immunology 10 (3), 210-215, 2010 | 2022 | 2010 |
The NLRP3 inflammasome: a sensor for metabolic danger? K Schroder, R Zhou, J Tschopp Science 327 (5963), 296, 2010 | 1279 | 2010 |
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice AR Mridha, A Wree, AAB Robertson, MM Yeh, CD Johnson, ... Journal of hepatology 66 (5), 1037-1046, 2017 | 958 | 2017 |
The regulated retrotransposon transcriptome of mammalian cells GJ Faulkner, Y Kimura, CO Daub, S Wani, C Plessy, KM Irvine, ... Nature genetics 41 (5), 563-571, 2009 | 910 | 2009 |
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo MK Chang, LJ Raggatt, KA Alexander, JS Kuliwaba, NL Fazzalari, ... The Journal of Immunology 181 (2), 1232-1244, 2008 | 797 | 2008 |
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition RC Coll, JR Hill, CJ Day, A Zamoshnikova, D Boucher, NL Massey, ... Nature chemical biology 15 (6), 556-559, 2019 | 775 | 2019 |
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ... Science translational medicine 10 (465), eaah4066, 2018 | 662 | 2018 |
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity D Boucher, M Monteleone, RC Coll, KW Chen, CM Ross, JL Teo, ... Journal of Experimental Medicine 215 (3), 827-840, 2018 | 543 | 2018 |
Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps KW Chen, M Monteleone, D Boucher, G Sollberger, D Ramnath, ... Science immunology 3 (26), eaar6676, 2018 | 535 | 2018 |
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, ... Cell Death & Differentiation 20 (9), 1149-1160, 2013 | 529 | 2013 |
Expression analysis of G Protein-Coupled Receptors in mouse macrophages JE Lattin, K Schroder, AI Su, JR Walker, J Zhang, T Wiltshire, K Saijo, ... Immunome research 4, 1-13, 2008 | 502 | 2008 |
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans CA Wells, JA Salvage-Jones, X Li, K Hitchens, S Butcher, RZ Murray, ... The Journal of Immunology 180 (11), 7404-7413, 2008 | 495 | 2008 |
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ... Immunity 45 (4), 761-773, 2016 | 473 | 2016 |
The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge KW Chen, CJ Groß, FV Sotomayor, KJ Stacey, J Tschopp, MJ Sweet, ... Cell reports 8 (2), 570-582, 2014 | 448 | 2014 |
Tiny RNAs associated with transcription start sites in animals RJ Taft, EA Glazov, N Cloonan, C Simons, S Stephen, GJ Faulkner, ... Nature genetics 41 (5), 572-578, 2009 | 439 | 2009 |
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ... Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017 | 437 | 2017 |
Differential expression of NLRP3 among hematopoietic cells G Guarda, M Zenger, AS Yazdi, K Schroder, I Ferrero, P Menu, A Tardivel, ... The Journal of Immunology 186 (4), 2529-2534, 2011 | 432 | 2011 |