| Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases D Rufino-Ramos, PR Albuquerque, V Carmona, R Perfeito, RJ Nobre, ... Journal of Controlled Release 262, 247-258, 2017 | 407 | 2017 |
| Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse R Perfeito, T Cunha-Oliveira, AC Rego Free Radical Biology and Medicine 53 (9), 1791-1806, 2012 | 138 | 2012 |
| Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells. R Perfeito, D Lázaro, T Outeiro, AC Rego Molecular and Cellular Neurosicences 62, 51-9, 2014 | 114 | 2014 |
| Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ... Stem cell reports 12 (5), 878-889, 2019 | 99 | 2019 |
| Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse R Perfeito, T Cunha-Oliveira, AC Rego Free Radical Biology and Medicine 62, 186-201, 2013 | 91 | 2013 |
| Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells R Perfeito, M Ribeiro, AC Rego Archives of toxicology 91, 1245-1259, 2017 | 46 | 2017 |
| The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ... Cell Reports 37 (3), 2021 | 34 | 2021 |
| Trolox protection of myelin membrane in hydrogen peroxide-treated mature oligodendrocytes R Perfeito, J Pereira, CR Oliveira, J Bettencourt-Relvas, A Cristina Rego Free radical research 41 (4), 444-451, 2007 | 22 | 2007 |
| Papel da alfa-sinucleína e da disfunção mitocondrial associada à doença de Parkinson R Perfeito, AC Rego Revista Neurociências 20 (2), 273-284, 2012 | 21 | 2012 |
| Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3 D Rufino-Ramos, PR Albuquerque, K Leandro, V Carmona, IM Martins, ... Molecular Therapy 31 (5), 1275-1292, 2023 | 20 | 2023 |
| Stem cell-based therapies for polyglutamine diseases LS Mendonça, I Onofre, CO Miranda, R Perfeito, C Nóbrega, ... Polyglutamine Disorders, 439-466, 2018 | 19 | 2018 |
| Expanded and wild-type Ataxin-3 modify the redox status of SH-SY5Y cells overexpressing α-synuclein C Noronha, R Perfeito, M Laço, U Wüllner, AC Rego Neurochemical research 42, 1430-1437, 2017 | 9 | 2017 |
| Interplay between alpha-synuclein and oxidative stress in Parkinson’s disease cell models R Perfeito Universidade de Coimbra, 2012 | 2 | 2012 |
| Post-translational modifications of alpha-synuclein and mitochondrial dysfunction in Parkinson’s disease R Perfeito, AC Rego Outeiro. T., ed.) Transworld Research Network, 203-230, 2008 | 1 | 2008 |
| Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease (MJD)/Spinocerebellar Ataxia type-3 (SCA3) D Rufino-Ramos, K Leandro, P Albuquerque, V Carmona, I Martins, ... HUMAN GENE THERAPY 33 (23-24), A178-A178, 2022 | | 2022 |
| Systemic delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of Machado-Joseph disease: a promising therapeutic strategy B Serra, SP Duarte, N Cartier, S Alves, LP de Almeida, R Perfeito HUMAN GENE THERAPY 33 (23-24), A85-A85, 2022 | | 2022 |
| Extracellular vesicles for therapy of spinocerebellar ataxia type 3 D Rufino-Ramos, V Carmona, IM Martins, M Barreira, PR Albuquerque, ... HUMAN GENE THERAPY 30 (11), A101-A101, 2019 | | 2019 |
| Intersection of autophagy and exosome secretion on alpha-synuclein spreading pattern in in vitro models of Parkinson's disease R Perfeito, V Anjos, RJ Nobre, M Garrido, J Schwamborn, LP de Almeida EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 87-88, 2019 | | 2019 |
| Optimization of a size-exclusion chromatography protocol to isolate plasma-derived extracellular vesicles for transcriptional biomarkers research L Gaspar, MM Santana, R Perfeito, P Albuquerque, TM Ribeiro-Rodrigues, ... Journal of Extracellular Vesicles 7, 151-152, 2018 | | 2018 |
| Autophagy activation prevents alpha-synuclein secretion in exosomes R Perfeito, V Anjos, RJ Nobre, M Garrido, LP de Almeida Journal of Extracellular Vesicles 5, PT6.01, 2016 | | 2016 |
Luis Pereira de AlmeidaUniversity of Coimbra, CNC - Center for Neuroscience and Cell Biology & Faculty of Pharmacy & CIBBVerified email at cnc.uc.pt
