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Robert Lyle McPherson
Robert Lyle McPherson
Verified email at mit.edu
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Cited by
Year
ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
RL McPherson, R Abraham, E Sreekumar, SE Ong, SJ Cheng, VK Baxter, ...
Proceedings of the National Academy of Sciences 114 (7), 1666-1671, 2017
1712017
ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication
R Abraham, D Hauer, RL McPherson, A Utt, IT Kirby, MS Cohen, A Merits, ...
Proceedings of the National Academy of Sciences 115 (44), E10457-E10466, 2018
1222018
ENPP1 processes protein ADP‐ribosylation in vitro
L Palazzo, CM Daniels, JE Nettleship, N Rahman, RL McPherson, ...
The FEBS journal 283 (18), 3371-3388, 2016
762016
ELTA: enzymatic labeling of terminal ADP-ribose
Y Ando, E Elkayam, RL McPherson, M Dasovich, SJ Cheng, J Voorneveld, ...
Molecular cell 73 (4), 845-856. e5, 2019
552019
Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases
AKL Leung, RL McPherson, DE Griffin
PLoS pathogens 14 (3), e1006864, 2018
512018
Both ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain affect neurovirulence in mice
R Abraham, RL McPherson, M Dasovich, M Badiee, AKL Leung, ...
MBio 11 (1), 10.1128/mbio. 03253-19, 2020
442020
High-throughput activity assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain
M Dasovich, J Zhuo, JA Goodman, A Thomas, RL McPherson, ...
ACS chemical biology 17 (1), 17-23, 2021
332021
Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly (ADP-ribosyl) ated proteins
P Thirawatananond, RL McPherson, J Malhi, S Nathan, MJ Lambrecht, ...
Scientific reports 9 (1), 5940, 2019
172019
ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4
RG Hammond, N Schormann, RL McPherson, AKL Leung, ...
Proceedings of the National Academy of Sciences 118 (2), e2004500118, 2021
62021
Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host–microbe interactions with oral commensals
S Ghosh, CP Ahearn, CR Isabella, VM Marando, GJ Dodge, H Bartlett, ...
Proceedings of the National Academy of Sciences 120 (22), e2216304120, 2023
42023
Lectin-Seq: a method to profile lectin-microbe interactions in native communities
RL McPherson, CR Isabella, RL Walker, D Sergio, S Bae, T Gaca, ...
Science Advances 9 (30), eadd8766, 2023
32023
Ion-pairing with triethylammonium acetate improves solid-phase extraction of ADP-ribosylated peptides
RL McPherson, SE Ong, AKL Leung
Journal of proteome research 19 (2), 984-990, 2019
32019
Application of human oral lectin ZG16B as a microbial glycan analysis probe (mGAP) to decode host-microbe interactions
S Ghosh, C Ahearn, C Isabella, V Marando, G Dodge, R McPherson, ...
Journal of Biological Chemistry 299 (3), S389, 2023
2023
Application of human oral lectin ZG16B as a microbial glycan analysis probe (mGAP) to decode host-microbe interactions
S Ghosh, CP Ahearn, CR Isabella, VM Marando, GJ Dodge, H Bartlett, ...
GLYCOBIOLOGY 32 (11), 1043-1043, 2022
2022
Methods and uses of enzymatic labeling of adp-ribose containing molecules
AKL Leung, Y Ando, RL McPherson, M Badiee, E Elkayam
US Patent App. 17/044,913, 2021
2021
High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain (preprint)
MA Dasovich, J Zhou, AG Thomas, JA Goodman, RL McPherson, ...
2021
Biochemical and proteomic investigations on the role of ADP-ribosylation in viral infection
RL McPherson
Johns Hopkins University, 2019
2019
Preparation of recombinant Alphaviruses for functional studies of ADP-ribosylation
R Abraham, RL McPherson, E Sreekumar, AKL Leung, DE Griffin
ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 297-316, 2018
2018
Quantitative determination of MAR hydrolase residue specificity in vitro by tandem mass spectrometry
RL McPherson, SE Ong, AKL Leung
ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 271-283, 2018
2018
Protein engineering of the decapping enzyme NudT16 enhances its ability to hydrolyze protein-conjugated ADP-ribose for post-translational site identification via mass spectrometry
P Thirawatananond, RL McPherson, JK Malhi, AK Leung, SB Gabelli
Cancer Research 77 (13_Supplement), 2212-2212, 2017
2017
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Articles 1–20