Aaron D. Gitler
Aaron D. Gitler
Professor of Genetics, Stanford University
Verified email at
Cited by
Cited by
α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ...
Science 313 (5785), 324-328, 2006
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
HJ Kim, NC Kim, YD Wang, EA Scarborough, J Moore, Z Diaz, ...
Nature 495 (7442), 467-473, 2013
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ...
Nature 466 (7310), 1069-1075, 2010
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ...
Science 347 (6229), 1436-1441, 2015
Stress granules as crucibles of ALS pathogenesis
YR Li, OD King, J Shorter, AD Gitler
Journal of cell biology 201 (3), 361-372, 2013
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler
Journal of Biological Chemistry 284 (30), 20329-20339, 2009
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
OD King, AD Gitler, J Shorter
Brain research 1462, 61-80, 2012
Neurodegenerative disease: models, mechanisms, and a new hope
AD Gitler, P Dhillon, J Shorter
Disease models & mechanisms 10 (5), 499-502, 2017
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
AD Gitler, BJ Bevis, J Shorter, KE Strathearn, S Hamamichi, LJ Su, ...
Proceedings of the National Academy of Sciences 105 (1), 145-150, 2008
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ...
Nature neuroscience 18 (9), 1226-1229, 2015
α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
AD Gitler, A Chesi, ML Geddie, KE Strathearn, S Hamamichi, KJ Hill, ...
Nature genetics 41 (3), 308-315, 2009
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1267-1288, 2018
A suite of Gateway® cloning vectors for high‐throughput genetic analysis in Saccharomyces cerevisiae
S Alberti, AD Gitler, S Lindquist
Yeast 24 (10), 913-919, 2007
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
LA Becker, B Huang, G Bieri, R Ma, DA Knowles, P Jafar-Nejad, ...
Nature 544 (7650), 367-371, 2017
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS
Z Sun, Z Diaz, X Fang, MP Hart, A Chesi, J Shorter, AD Gitler
PLoS biology 9 (4), e1000614, 2011
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
BS Johnson, JM McCaffery, S Lindquist, AD Gitler
Proceedings of the National Academy of Sciences 105 (17), 6439-6444, 2008
Defects in trafficking bridge Parkinson's disease pathology and genetics
A Abeliovich, AD Gitler
Nature 539 (7628), 207-216, 2016
A yeast functional screen predicts new candidate ALS disease genes
J Couthouis, MP Hart, J Shorter, M DeJesus-Hernandez, R Erion, ...
Proceedings of the National Academy of Sciences 108 (52), 20881-20890, 2011
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
Semaphorin-plexin signaling guides patterning of the developing vasculature
J Torres-Vázquez, AD Gitler, SD Fraser, JD Berk, VN Pham, MC Fishman, ...
Developmental cell 7 (1), 117-123, 2004
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